Bench-to-bedside review: Mechanisms of critical illness–classifying microcirculatory flow abnormalities in distributive shock

PWG Elbers, C Ince - Critical care, 2006 - Springer
Over 30 years ago Weil and Shubin proposed a re-classification of shock states and
identified hypovolemic, cardiogenic, obstructive and distributive shock. The first three …

Plasma viscosity regulates systemic and microvascular perfusion during acute extreme anemic conditions

P Cabrales, AG Tsai - American Journal of Physiology …, 2006 - journals.physiology.org
The hamster window chamber model was used to study systemic and microvascular
hemodynamic responses to extreme hemodilution with low-and high-viscosity plasma …

Maximum aerobic performance in lines of Mus selected for high wheel-running activity: effects of selection, oxygen availability and the mini-muscle phenotype

EL Rezende, T Garland Jr… - Journal of …, 2006 - journals.biologists.com
We compared maximum aerobic capacity during forced exercise (V̇ O2max) in hypoxia (P
O2= 14% O2), normoxia (21%) and hyperoxia (30%) of lines of house mice selectively bred …

Blood viscosity maintains microvascular conditions during normovolemic anemia independent of blood oxygen-carrying capacity

P Cabrales, J Martini, M Intaglietta… - American Journal of …, 2006 - journals.physiology.org
Responses to exchange transfusion with red blood cells (RBCs) containing methemoglobin
(MetRBC) were studied in an acute isovolemic hemodiluted hamster window chamber …

Microvascular perspective of oxygen-carrying and-noncarrying blood substitutes

M Intaglietta, P Cabrales, AG Tsai - Annu. Rev. Biomed. Eng., 2006 - annualreviews.org
The development of an alternative to natural blood has evolved from the initial goal of
replicating blood properties to the current objective of formulating a fluid that can be used to …

Nitric oxide regulation of microvascular oxygen exchange during hypoxia and hyperoxia

P Cabrales, AG Tsai… - Journal of Applied …, 2006 - journals.physiology.org
The objective of this work was to test the hypothesis that the limitation of nitric oxide (NO)
availability accentuates microvascular reactivity to oxygen. The awake hamster chamber …

Microvascular effects following treatment with polyethylene glycol-albumin in lipopolysaccharide-induced endotoxemia

N Hangai-Hoger, P Nacharaju, BN Manjula… - Critical care …, 2006 - journals.lww.com
Objective: To determine whether resuscitation with polyethylene glycol conjugated bovine
serum albumin (2.5% weight/volume) infused at 16 mL/kg/hr (PEG-BSA-16) or at 24 …

Resuscitation of severe but brief haemorrhagic shock with PFC in rabbits restores skeletal muscle oxygen delivery and does not alter skeletal muscle metabolism

S Audonnet-Blaise, MP Krafft, Y Smani, PM Mertes… - Resuscitation, 2006 - Elsevier
Studies have demonstrated that perfluorocarbon (PFC) emulsions associated with hyperoxia
improved whole body oxygen delivery during resuscitation of acute haemorrhagic shock …

Effects of a new perfluorocarbon emulsion on human plasma and whole‐blood viscosity in the presence of albumin, hydroxyethyl starch, or modified fluid gelatin: an in …

V Jouan‐Hureaux, S Audonnet‐Blaise… - …, 2006 - Wiley Online Library
BACKGROUND: Artificial oxygen carriers such as perfluorocarbon (PFC) emulsions have
reached Phase III clinical trials as alternatives to homologous blood, but their rheologic …

[PDF][PDF] BLOOD CONSERVATION AND TRANSFUSION ALTERNATIVES

V Jouan-Hureaux, S Audonnet-Blaise, D Lacatusu… - …, 2006 - academia.edu
BACKGROUND: Artificial oxygen carriers such as perfluorocarbon (PFC) emulsions have
reached Phase III clinical trials as alternatives to homologous blood, but their rheologic …