The Role of K+ Channels in Determining Pulmonary Vascular Tone, Oxygen Sensing, Cell Proliferation, and Apoptosis: Implications in Hypoxic Pulmonary …

R Moudgil, ED Michelakis, SL Archer - Microcirculation, 2006 - Taylor & Francis
Potassium channels are tetrameric, membrane-spanning proteins that selectively conduct
K+ at near diffusion-limited rates. Their remarkable ionic selectivity results from a highly …

G protein-activated inwardly rectifying potassium channels as potential therapeutic targets

T Kobayashi, K Ikeda - Current pharmaceutical design, 2006 - ingentaconnect.com
G protein-activated inwardly rectifying K+(GIRK; Kir3) channels regulate the neuronal activity
and heart rate. Molecular cloning of the GIRK channel genes has led to remarkable progress …

Tertiapin, a selective IKACh blocker, terminates atrial fibrillation with selective atrial effective refractory period prolongation

N Hashimoto, T Yamashita, N Tsuruzoe - Pharmacological research, 2006 - Elsevier
It is well known that vagal nerve tone plays a crucial role in atrial fibrillation (AF).
Acetylcholine-activated potassium current (IKACh) mediates much of the cardiac response …

[HTML][HTML] Inhibition of G protein-activated inwardly rectifying K+ channels by ifenprodil

T Kobayashi, K Washiyama, K Ikeda - Neuropsychopharmacology, 2006 - nature.com
G protein-activated inwardly rectifying K+ channels (GIRK, also known as Kir3) are regulated
by various G-protein-coupled receptors. Activation of GIRK channels plays an important role …

Inhibition of G protein-activated inwardly rectifying K+ channels by the antidepressant paroxetine

T Kobayashi, K Washiyama, K Ikeda - Journal of pharmacological sciences, 2006 - Elsevier
Paroxetine is commonly used as a selective serotonin reuptake inhibitor for the treatment of
depression and other psychiatric disorders. However, the molecular mechanisms of the …

Method of using cells expressing galanin receptor 3 (GALR3)

JA Bard, B Borowsky, KE Smith, TA Branchek… - US Patent …, 2006 - Google Patents
US7022489B2 - Method of using cells expressing galanin receptor 3 (GALR3) - Google
Patents US7022489B2 - Method of using cells expressing galanin receptor 3 (GALR3) …

[PDF][PDF] 흰쥐간성상(이토) 세포의내향성포타슘전류특성및배양에따른변화

이동현 - 2006 - ir.ymlib.yonsei.ac.kr
[한글] 간 성상세포는 여러 병적 상황에서 아근섬유세포나 평활근세포와 유사한 형태로
전환함으로써 만성 간질환에서의 혈관저항 증가 및 간문맥 고혈압 형성에 관여하고 있음이 …

DNA encoding SNORF33 receptor

BE Borowsky, KL Ogozalek, KA Jones - US Patent 6,987,005, 2006 - Google Patents
This invention provides isolated nucleic acids encoding mammalian SNORF33 receptors,
purified mammalian SNORF33 receptors, vectors comprising nucleic acid encod ing …

Method of inhibiting inward rectifier, G-protein activated, mammalian, potassium channels and uses thereof

HA Lester, N Davidson, P Kofuji - US Patent 7,138,248, 2006 - Google Patents
Compositions and methods are provided for producing func tional mammalian inward
rectifier, G-protein activated potassium channels (Kir3. 0 channels). A channel is a mul …

[PDF][PDF] Der Einfluß der porenbildenden Untereinheit des KATP-Kanals auf die pharmakologischen Eigenschaften der Sulfonylharnstoffrezeptoren SUR1 und SUR2A …

S Bieger - 2006 - bibliographie.uni-tuebingen.de
3.1. 2.1 Verdrängung von 3 H-GBC durch Glibornurid 79 3.1. 2.2 Verdrängung von 3 H-GBC
durch Nateglinid 81 3.1. 3 Bindung von Typ B Liganden an SUR1 und Kir6. 2/SUR1 …