Transplantation of microencapsulated cells is proposed as a therapy for the treatment of a
wide variety of diseases since it allows for transplantation of endocrine cells in the absence …

Cell microencapsulation holds promise for the treatment of many diseases by the continuous
delivery of therapeutic products. The biocompatibility of the microcapsules and their …

Alginate, a polysaccharide extracted from brown seaweed, is widely used for the
microencapsulation of islets of Langerhans, allowing their transplantation without …

Implantation of microencapsulated cells has been proposed as a therapy for a wide variety
of diseases. An absolute requirement is that the applied microcapsules have an optimal …

We have developed a novel biodegradable, polymeric fiber construct that is coextruded
using a wet‐spinning process into a core‐sheath format with a polysaccharide pre‐hydrogel …

This paper presents the concept and most of the research undertaken all over the world for
the development of a bio‐artificial pancreas (BAP) device over the last 30 years. The …

Alginate is frequently used for cell encapsulation, but its biocompatibility is neither optimal
nor reproducible. Purifying the alginate is critical for achieving a suitable biocompatibility …

The long-term durability of agarose microencapsulated islets against autoimmunity was
evaluated in NOD mice. Islets were isolated from 6-8-week-old prediabetic male NOD mice …

Mammalian cell encapsulation is under investigation for the treatment of a wide variety of
diseases, since it allows for transplantation of endocrine cells in the absence of undesired …

Encapsulation of pancreatic islets in alginate is used to protect against xenogenic rejection
in different animal models. In this study, several factors, including differences in alginate …