Beyond the dogma: novel β2-adrenoceptor signalling in the airways
MA Giembycz, R Newton - European Respiratory Journal, 2006 - Eur Respiratory Soc
β2-Adrenoceptor agonists evoke rapid bronchodilatation and are the mainstay of the
treatment of asthma symptoms worldwide. The mechanism of action of this class of …
treatment of asthma symptoms worldwide. The mechanism of action of this class of …
New therapies for asthma
PJ Barnes - Trends in molecular medicine, 2006 - cell.com
Asthma is an increasing global health problem, and many patients continue to suffer from
chronic symptoms. However, current therapy with inhaled corticosteroids and a long-acting …
chronic symptoms. However, current therapy with inhaled corticosteroids and a long-acting …
The effective treatment of COPD: anticholinergics and what else?
M Cazzola, MG Matera - Drug Discovery Today: Therapeutic Strategies, 2006 - Elsevier
Long-acting bronchodilator therapy should be considered when a COPD patient is
symptomatic. For patients whose conditions are not sufficiently controlled by monotherapy …
symptomatic. For patients whose conditions are not sufficiently controlled by monotherapy …
Emerging drugs for the treatment of chronic obstructive pulmonary disease
By 2020 chronic obstructive pulmonary disease (COPD) will be the third leading cause of
mortality and fifth leading cause of morbidity. Research over the past two decades has shed …
mortality and fifth leading cause of morbidity. Research over the past two decades has shed …
Biological targets for therapeutic interventions in COPD: clinical potential
G Pelaia, A Vatrella, L Gallelli, T Renda… - … Journal of Chronic …, 2006 - Taylor & Francis
COPD is a widespread inflammatory respiratory disorder characterized by a progressive,
poorly reversible airflow limitation. Currently available therapies are mostly based on those …
poorly reversible airflow limitation. Currently available therapies are mostly based on those …
Progress in the development of Inhaled, long-acting β2-adrenoceptor agonists
PA Glossop, DA Price - Annual Reports in Medicinal Chemistry, 2006 - Elsevier
Publisher Summary Long acting β 2-adrenoceptor agonists are a highly precedented drug
class used for the treatment of asthma and chronic obstructive pulmonary disease (COPD) …
class used for the treatment of asthma and chronic obstructive pulmonary disease (COPD) …
Are there any realistic chances to develop new drugs for asthma?
A Amon, A Pahl, I Szelenyi - Drug News & Perspectives, 2006 - europepmc.org
Asthma bronchiale, an inflammatory airway disease, imposes a significant health care
problem worldwide. It is characterized by three critical phenotypic traits: intermittent and …
problem worldwide. It is characterized by three critical phenotypic traits: intermittent and …
Glycopyrrolate combinations for the treatment of respiratory diseases: Sofotec GmbH & Co. KG: US20050175548, US20050175549 & US20050175547
A Guerra, NE Campillo, JA Páez - Expert Opinion on Therapeutic …, 2006 - Taylor & Francis
This paper analyses three patents, published in 2005 by Sofotec GmbH & Co. KG, for the
treatment of respiratory diseases that include asthma and chronic obstructive pulmonary …
treatment of respiratory diseases that include asthma and chronic obstructive pulmonary …
Effects of asthma treatment: the present and future
GP Currie - Expert Review of Clinical Immunology, 2006 - Taylor & Francis
The increasing burden of asthma in both primary and secondary care has led to extensive
research into its genetics, pathophysiology and treatment over the past few decades …
research into its genetics, pathophysiology and treatment over the past few decades …
Long-acting β2 agonists: Pfizer: US20050171147 & US20050182091
P Norman - Expert Opinion on Therapeutic Patents, 2006 - Taylor & Francis
Two applications claim very closely related arylsulfonamide β2-agonists. The basic generic
claim is the same in both cases with subsidiary claims covering different permutations of the …
claim is the same in both cases with subsidiary claims covering different permutations of the …