Food intake, energy expenditure and body adiposity are homeostatically regulated. Central
and peripheral signals communicate information about the current state of energy balance to …

The role of gastrointestinal hormones in the regulation of appetite is reviewed. The
gastrointestinal tract is the largest endocrine organ in the body. Gut hormones function to …

Background: Oxyntomodulin has recently been found to decrease body-weight in obese
humans and may be a potential anti-obesity therapy. Objective: To determine whether …

The control of food intake and body weight by the brain relies upon the detection and
integration of signals reflecting energy stores and fluxes, and their interaction with many …

There is a growing worldwide epidemic of obesity. Obese people have a higher incidence of
type 2 diabetes and cardiovascular disease, and hence present increasing social, financial …

Gut hormones signal to the central nervous system to influence energy homeostasis.
Evidence supports the existence of a system in the gut that senses the presence of food in …

This review provides a summary of currently available pharmaceutical therapies for the
treatment of obesity, along with an overview of the pipeline of products currently in …

The glycaemic index (GI) is a measure of the ability of a food to raise blood sugar. Written by
one of the co-inventors of the term, this is a clear and balanced review of current knowledge …

Reproductive function declines at both extremes of human energy balance. The relationship
between obesity and reproductive function is complex and incompletely understood. The …

The worsening global obesity epidemic, particularly the increase in childhood obesity, has
prompted research into the mechanisms of appetite regulation. Complex pathways modulate …