Thrombotic microangiopathy (TMA) is a microvascular occlusive disorder characterized by
predominantly platelet thrombi in the renal and/or systemic circulations. Haemolytic uraemic …

Thrombotic microangiopathy, which includes thrombotic thrombocytopenic purpura (TTP),
shiga-toxin-associated hemolytic uremic syndrome (Stx-HUS) and atypical HUS, is …

We have established a new, enzyme-linked immunosorbent assay (ELISA) for the detection
of ADAMTS13 antigen using purified polyclonal rabbit anti-human ADAMTS13 IgG. Normal …

Recent advances have demonstrated that thrombotic thrombocytopenic purpura (TTP),
characterized by widespread thrombosis in the arterioles and capillaries, is caused by …

The concept of “probable” antiphospholipid syndrome (APS) is almost identical with several
conditions which may presage the development of the APS with its major complications of …

Von Willebrand factor (VWF) is a glycoprotein that plays an important role in the primary
hemostatic process by inducing platelet adhesion and aggregation at sites of vascular injury …

Background: Many patients with acquired thrombotic thrombocytopenic purpura (TTP)
harbor autoantibodies that may bind and/or inhibit ADAMTS-13 proteolytic activity and …

Thrombotic thrombocytopenic purpura (TTP) is a disease characterized by microvascular
thrombosis, often associated with deficiency of the von Willebrand factor (VWF) cleaving …

Antibodies directed against ADAMTS13 have been detected in the majority of patients with
acquired thrombotic thrombocytopenic purpura (TTP). We have previously localized a major …

Functional assays are commonly used to measure the antibodies of ADAMTS13 found in
patients of thrombotic thrombocytopenic purpura (TTP). In this study we used an enzyme …