Role of oxidative stress in experimental sepsis and multisystem organ dysfunction

E Crimi, V Sica, AS Slutsky, H Zhang… - Free radical …, 2006 - Taylor & Francis
Massive increase in radical species can lead to oxidative stress, promoting cell injury and
death. This review focuses on experimental evidence of oxidative stress in critical illnesses …

Imbalance in SOD/CAT activities in rat skeletal muscles submitted to treadmill training exercise

RA Pinho, ME Andrades, MR Oliveira, AC Pirola… - Cell Biology …, 2006 - Elsevier
The association between physical exercise and oxidative damage in the skeletal
musculature has been the focus of many studies in literature, but the balance between …

Biomarkers of oxidative stress in critically ill patients: what should be measured, when and how?

T Lemineur, G Deby-Dupont… - Current Opinion in Clinical …, 2006 - journals.lww.com
The assessment of oxidative stress, defined as the association between an increased
production of oxygen-derived species and an exhaustion of the stores of antioxidants …

Different effects of endotoxic shock on the respiratory function of liver and heart mitochondria in rats

AV Kozlov, K Staniek, S Haindl… - American Journal …, 2006 - journals.physiology.org
This study was designed to clarify whether mitochondrial function/dysfunction and reactive
oxygen species (ROS) production have a temporal relationship with organ failure during …

Proteomic analysis of altered protein expression in skeletal muscle of rats in a hypermetabolic state induced by burn sepsis

X Duan, F Berthiaume, D Yarmush… - Biochemical …, 2006 - portlandpress.com
mRNA profiling has been extensively used to study muscle wasting. mRNA level changes
may not reflect that of proteins, especially in catabolic muscle where there is decreased …

[HTML][HTML] Total hydroperoxide and biological antioxidant potentials in a neonatal sepsis model

H Kakita, MH Hussein, GA Daoud, T Kato, H Murai… - Pediatric …, 2006 - nature.com
Oxidant/antioxidant imbalance plays an important role in septic shock. The present study
examined changes in circulating oxidative components in a neonatal sepsis model. Subjects …

[HTML][HTML] Endotoxin-induced myocardial dysfunction in senescent rats

S Rozenberg, S Besse, H Brisson, E Jozefowicz… - Critical Care, 2006 - Springer
Introduction Aging is associated with a decline in cardiac contractility and altered immune
function. The aim of this study was to determine whether aging alters endotoxin-induced …

Validation of a Pseudomonas aeruginosa porcine model of septic shock

T Rimmelé, A Assadi, F Benatir, E Boselli, C Kaminski… - Journal of Infection, 2006 - Elsevier
OBJECTIVES: To develop a standardized bacteraemic porcine model of septic shock with
cardiovascular and immunological profiles similar to those observed in human clinical …

Parâmetros oxidativos plasmáticos na determinação do desfecho e resposta ao tratamento com antioxidantes na sepse

MO Guerreiro - 2006 - lume.ufrgs.br
OBJETIVOS: determinar a relação entre parâmetros de estresse oxidativo, gravidade de
sepse e resposta ao tratamento com antioxidantes. MATERIAL E MÉTODOS: foram …

[引用][C] 丙酮酸乙酯调节脓毒症小鼠炎症反应的研究

陈敏英, 梁力建, 欧阳彬, 管向东, 徐鸿绪, 陈娟 - 中华实验外科杂志, 2006