Mammalian target of rapamycin (mTOR) regulates both proliferation of megakaryocyte progenitors and late stages of megakaryocyte differentiation

H Raslova, V Baccini, L Loussaief, B Comba… - Blood, 2006 - ashpublications.org
A major determinant in platelet production is the megakaryocyte (MK) size that is regulated
both by ploidization and the increase in cytoplasmic volume at the end of maturation. Here …

Transcriptional regulation of megakaryopoiesis: thrombopoietin signaling and nuclear factors

K Kirito, K Kaushansky - Current opinion in hematology, 2006 - journals.lww.com
Transcriptional regulation of megakaryopoiesis: thrombopoiet... : Current Opinion in
Hematology Transcriptional regulation of megakaryopoiesis: thrombopoietin signaling and …

Molecular regulation of Megakaryopoiesis: the role of Fli-1 and IFI16

LN Johnson - 2006 - unsworks.unsw.edu.au
Megakaryocytes (Mks) are unique bone marrow cells, which produce platelets.
Dysregulated Mk development can lead to abnormal platelet number and the production of …

[图书][B] Structural and functional characterization of Runx1 point mutations identified in leukemia and cleidocranial dysplasia patients

C Matheny - 2006 - search.proquest.com
Core binding factors are heterodimeric transcription factors involved in diverse
developmental processes. They consist of a DNA binding Runx subunit and a non-DNA …