The dystrophin–glycoprotein complex (DGC) can be considered as a specialized adhesion
complex, linking the extracellular matrix to the actin cytoskeleton, primarily in muscle cells …

Reduced homeostatic capacity for intracellular Ca2+ ([Ca2+] i) movement may underlie the
progression of sarcopenia and contractile dysfunction during muscle aging. We report two …

The phenomenon of calcium microdomains is firmly established in the field of subcellular
physiology. These regions of localized, transient calcium increase are exemplified by the …

Dantrolene reduces the elevated myoplasmic Ca 2+ generated during malignant
hyperthermia, a pharmacogenetic crisis triggered by volatile anesthetics. Although specific …

In vivo, severe hypoglycemia is frequently associated with seizures. The hippocampus is a
structure prone to develop seizures and seizure‐induced damage. Patients with repeated …

The cytosolic Ca2+-binding protein regucalcin is involved in intracellular signaling and
present in high abundance in the liver. Here, we could show by comparative mass …

We developed an algorithm for the automated detection and analysis of elementary Ca 2+
release events (ECRE) based on the two-dimensional nondecimated wavelet transform. The …

Ca 2+ sparks are the elementary units of intracellular Ca 2+ signaling in striated muscle
cells revealed as localized Ca 2+ release events from sarcoplasmic reticulum (SR) by …

Friedrich O, Wegner FV, Hartamann M, Frey B, Sommer K, Ludwig H, Fink RHA.'In situ'high
pressure confocal Ca2+-fluorescence microscopy in skeletal muscle: a new method to study …

Aim: To study whether the volume of cardiomyocytes and their functions would change
under severe pathological conditions or osmotic stress. To clarify the role of ryanodine …