Endothelial dysfunction: a comprehensive appraisal

RJ Esper, RA Nordaby, JO Vilariño, A Paragano… - Cardiovascular …, 2006 - Springer
The endothelium is a thin monocelular layer that covers all the inner surface of the blood
vessels, separating the circulating blood from the tissues. It is not an inactive organ, quite the …

Circulating markers of endothelial function in cardiovascular disease

J Constans, C Conri - Clinica chimica acta, 2006 - Elsevier
Endothelial dysfunction is a key event in cardiovascular disease. Measurement of
endothelial dysfunction in vivo presents a major challenge, but has important implications …

Low serum bilirubin levels are independently and inversely related to impaired flow-mediated vasodilation and increased carotid intima-media thickness in both men …

D Erdogan, H Gullu, E Yildirim, D Tok, I Kirbas, O Ciftci… - Atherosclerosis, 2006 - Elsevier
BACKGROUND: Elevated levels of low-density lipoprotein (LDL) cholesterol and its
oxidative modification have been described to be involved in the process of atherogenesis …

Pre-eclampsia is associated with sleep-disordered breathing and endothelial dysfunction

D Yinon, L Lowenstein, S Suraya… - European …, 2006 - Eur Respiratory Soc
Pre-eclamptic toxaemia (PET) may be associated with both endothelial dysfunction (ED) and
sleep-disordered breathing (SDB). It was hypothesised that females with PET would …

[HTML][HTML] Novel aspects of endothelium-dependent regulation of vascular tone

IC Villar, S Francis, A Webb, AJ Hobbs, A Ahluwalia - Kidney international, 2006 - Elsevier
The vascular endothelium plays a crucial role in the regulation of vascular homeostasis and
in preventing the initiation and progress of cardiovascular disease by controlling mechanical …

Clinical methods for the evaluation of endothelial function–a focus on resistance arteries

R Joannides, J Bellien… - Fundamental & clinical …, 2006 - Wiley Online Library
Endothelial dysfunction is a key event in the pathophysiology of cardiovascular diseases
and appears as a strong independent predictor of cardiovascular events. In this context …

Variability of flow-mediated dilation measurements with repetitive reactive hyperemia

RA Harris, J Padilla, LD Rink… - Vascular …, 2006 - journals.sagepub.com
To capture the response of an acute intervention, multiple post intervention measurements
of flow-mediated dilation (FMD) must be performed. The effect of repetitive reactive …

Long-term thyrotropin-suppressive therapy with levothyroxine impairs small and large artery elasticity and increases left ventricular mass in patients with thyroid …

M Shargorodsky, S Serov, D Gavish, E Leibovitz… - Thyroid, 2006 - liebertpub.com
Background: Exogenous subclinical hyperthyroidism, caused by long-term thyrotropin (TSH)-
suppressive treatment with levothyroxine (LT4), is associated with several cardiovascular …

Coordinated regulation of endothelial nitric oxide synthase activity by phosphorylation and subcellular localization

YC Boo, HJ Kim, H Song, D Fulton, W Sessa… - Free Radical Biology and …, 2006 - Elsevier
Endothelial nitric oxide synthase (eNOS) is regulated by multiple mechanisms including
Ca2+/calmodulin binding, protein-protein interactions, phosphorylation, and subcellular …

Endoglin expression in the endothelium is regulated by Fli-1, Erg, and Elf-1 acting on the promoter and a–8-kb enhancer

JE Pimanda, WYI Chan, IJ Donaldson, M Bowen… - Blood, 2006 - ashpublications.org
Angiogenesis is critical to the growth and regeneration of tissue but is also a key component
of tumor growth and chronic inflammatory disorders. Endoglin plays a key role in …