Role of CYP pharmacogenetics and drug‐drug interactions in the efficacy and safety of atypical and other antipsychotic agents
M Murray - Journal of pharmacy and pharmacology, 2006 - Wiley Online Library
Cytochrome P450 (CYP) drug oxidases play a pivotal role in the elimination of antipsychotic
agents, and therefore influence the toxicity and efficacy of these drugs. Factors that affect …
agents, and therefore influence the toxicity and efficacy of these drugs. Factors that affect …
Multiple dose pharmacokinetics of risperidone and 9-hydroxyrisperidone in Chinese female patients with schizophrenia
Z Zhou, X Li, H Peng, X Yu, M Yang, F Su… - Acta Pharmacologica …, 2006 - nature.com
Aim: To study the multiple dose clinical pharmacokinetics of risperidone and its main active
metabolite, 9-hydroxyrisperidone, in Chinese female patients with schizophrenia. Methods …
metabolite, 9-hydroxyrisperidone, in Chinese female patients with schizophrenia. Methods …
[图书][B] Cytochrome P450 enzymes—in vitro, in vivo, and in silico studies
M Turpeinen - 2006 - oulurepo.oulu.fi
Metabolism is a major determinant of the pharmacokinetic properties of most drugs and is
often behind bioavailability problems, drug-drug interactions, and metabolic idiosyncrasies …
often behind bioavailability problems, drug-drug interactions, and metabolic idiosyncrasies …