Diabetes-induced mechanical hyperalgesia involves spinal mitogen-activated protein kinase activation in neurons and microglia via N-methyl-D-aspartate-dependent …

L Daulhac, C Mallet, C Courteix, M Etienne… - Molecular …, 2006 - ASPET
Molecular mechanisms underlying diabetes-induced painful neuropathy are poorly
understood. We have demonstrated, in rats with streptozotocin-induced diabetes, that …

Silencing of vanilloid receptor TRPV1 by RNAi reduces neuropathic and visceral pain in vivo

T Christoph, A Grünweller, J Mika, MKH Schäfer… - Biochemical and …, 2006 - Elsevier
RNA interference (RNAi) has proven to be a powerful technique to study the function of
genes by producing knock-down phenotypes. Here, we report that intrathecal injection of an …

Intermittent lumbar puncture in rats: a novel method for the experimental study of opioid tolerance

JJ Xu, BC Walla, MF Diaz, GN Fuller… - Anesthesia & …, 2006 - journals.lww.com
IMPLICATIONS: Chronic morphine administration via intermittent lumbar puncture in rats
induced analgesic tolerance while avoiding catheter-associated morbidity. This novel …

Inhibition of glutamate transporters increases the minimum alveolar concentration for isoflurane in rats

S Cechova, Z Zuo - BJA: British Journal of Anaesthesia, 2006 - academic.oup.com
Background. Glutamate transporters [also named excitatory amino acid transporters
(EAATs)] bind and take up extracellular glutamate, a major excitatory neurotransmitter, and …

Complexation of 50% enantiomeric excess (S75-R25) bupivacaine with cyclodextrins and spinal block anesthesia in rats

DR Araujo, AFA Braga, CM Moraes… - Revista Brasileira de …, 2006 - SciELO Brasil
JUSTIFICATIVA E OBJETIVOS: Com a finalidade de prolongar a duração de ação e reduzir
a toxicidade sistêmica, têm-se desenvolvido formulações de anestésicos locais (AL) …

[HTML][HTML] Mistura com excesso enantiomérico de 50%(S75-R25) de bupivacaína complexada com ciclodextrinas e anestesia por via subaracnóidea em ratos

DR Araujo, AFA Braga, CM Moraes… - Revista Brasileira de …, 2006 - SciELO Brasil
JUSTIFICATIVA E OBJETIVOS: Com a finalidade de prolongar a duração de ação e reduzir
a toxicidade sistêmica, têm-se desenvolvido formulações de anestésicos locais (AL) …

Pharmacological profiles of the novel analgesic M58996 in rat models of persistent and neuropathic pain

Y Akada, R Mori, K Matsuura, K Suzuki… - Journal of …, 2006 - jstage.jst.go.jp
We investigated the effects of 4-(N-{1-[2-(4-cyanophenyl) ethyl]-4-hydroxypiperidin-4-
ylmethyl}-N-methylamino) benzoic acid monohydrochloride (M58996), a novel analgesic, on …

[PDF][PDF] Le contrôle descendant ocytocinergique Modulation du système nociceptif et effet antinociceptif de l'ocytocine

MDM RAGGENBASS - 2006 - publication-theses.unistra.fr
Résumé Les couches superficielles de la moelle épinière constituent le premier relais
d'intégration des informations nociceptives périphériques véhiculées par les fibres …

[引用][C] 胞外信号调节激酶抑制剂对慢性压迫损伤大鼠痛觉过敏的作用

徐艳冰, 胡振华, 何建华, 曹君利, 张励才, 曾因明 - 中国行为医学科学, 2006

[引用][C] γ-氨基丁酸转运体抑制剂NO-711 术前鞘内注射对坐骨神经慢性挤压伤大鼠神经病理性痛觉过敏的影响

聂鑫, 朱珊珊, 曾因明 - 中国药理学通报, 2006