Biomarkers of cardiovascular disease: molecular basis and practical considerations
RS Vasan - Circulation, 2006 - Am Heart Assoc
echocardiogram) may be expected to facilitate the identification of patients with chest pain of
an ischemic etiology (angina). In a patient presenting to the emergency department with …
an ischemic etiology (angina). In a patient presenting to the emergency department with …
Positive natural selection in the human lineage
Positive natural selection is the force that drives the increase in prevalence of advantageous
traits, and it has played a central role in our development as a species. Until recently, the …
traits, and it has played a central role in our development as a species. Until recently, the …
[图书][B] Radiobiology for the Radiologist
EJ Hall, AJ Giaccia - 2006 - redjournal.org
Many refer to the textbook Radiobiology for the Radiologist as the “bible” of radiation biology
for educating residents, researchers, and clinicians. Dr. Eric Hall has compiled, written, and …
for educating residents, researchers, and clinicians. Dr. Eric Hall has compiled, written, and …
[HTML][HTML] A bivalent chromatin structure marks key developmental genes in embryonic stem cells
The most highly conserved noncoding elements (HCNEs) in mammalian genomes cluster
within regions enriched for genes encoding developmentally important transcription factors …
within regions enriched for genes encoding developmentally important transcription factors …
A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters
S Saxonov, P Berg, DL Brutlag - Proceedings of the …, 2006 - National Acad Sciences
A striking feature of the human genome is the dearth of CpG dinucleotides (CpGs)
interrupted occasionally by CpG islands (CGIs), regions with relatively high content of the …
interrupted occasionally by CpG islands (CGIs), regions with relatively high content of the …
Counting the zinc-proteins encoded in the human genome
C Andreini, L Banci, I Bertini… - Journal of proteome …, 2006 - ACS Publications
Metalloproteins are proteins capable of binding one or more metal ions, which may be
required for their biological function, or for regulation of their activities or for structural …
required for their biological function, or for regulation of their activities or for structural …
DNA methylation profiling of human chromosomes 6, 20 and 22
F Eckhardt, J Lewin, R Cortese, VK Rakyan, J Attwood… - Nature …, 2006 - nature.com
DNA methylation is the most stable type of epigenetic modification modulating the
transcriptional plasticity of mammalian genomes. Using bisulfite DNA sequencing, we report …
transcriptional plasticity of mammalian genomes. Using bisulfite DNA sequencing, we report …
[HTML][HTML] Alternative splicing: new insights from global analyses
BJ Blencowe - Cell, 2006 - cell.com
Recent analyses of sequence and microarray data have suggested that alternative splicing
plays a major role in the generation of proteomic and functional diversity in metazoan …
plays a major role in the generation of proteomic and functional diversity in metazoan …
Genetics and genomics of core short tandem repeat loci used in human identity testing
JM Butler - Journal of forensic sciences, 2006 - Wiley Online Library
Over the past decade, the human identity testing community has settled on a set of core
short tandem repeat (STR) loci that are widely used for DNA typing applications. A variety of …
short tandem repeat (STR) loci that are widely used for DNA typing applications. A variety of …
ERK1/2 MAP kinases in cell survival and apoptosis
Z Lu, S Xu - IUBMB life, 2006 - Wiley Online Library
ERK1/2 is an important subfamily of mitogen‐activated protein kinases that control a broad
range of cellular activities and physiological processes. ERK1/2 can be activated transiently …
range of cellular activities and physiological processes. ERK1/2 can be activated transiently …