Pathophysiology of acute ischaemic stroke: an analysis of common signalling mechanisms and identification of new molecular targets

N Mitsios, J Gaffney, P Kumar, J Krupinski, S Kumar… - Pathobiology, 2006 - karger.com
Stroke continues to be a major cause of death and disability. The currently available
therapies have proven to be highly unsatisfactory (except thrombolysis) and attempts are …

Can angiographic vasospasm be used as a surrogate marker in evaluating therapeutic interventions for cerebral vasospasm?

CP Nolan, RL Macdonald - Neurosurgical focus, 2006 - thejns.org
✓ The authors tested the null hypothesis that published literature with a high level of
evidence does not support the assertion that subarachnoid hemorrhage (SAH) causes …

Measurement of brain temperature with magnetic resonance spectroscopy in acute ischemic stroke

B Karaszewski, JM Wardlaw, I Marshall… - Annals of …, 2006 - Wiley Online Library
Objective Pyrexia is associated with poor outcome after stroke, but the temperature changes
in the brain after stroke are poorly understood. We used magnetic resonance spectroscopic …

Imaging of cerebral blood flow and metabolism

JP Coles - Current Opinion in Anesthesiology, 2006 - journals.lww.com
Imaging of cerebral blood flow and metabolism has been shown to be useful following a
variety of causes of brain injury, as it can help to define the cause and extent of injury …

Cerebral blood flow threshold of ischemic penumbra and infarct core in acute ischemic stroke: a systematic review

TY Lee, BD Murphy, RI Aviv, AJ Fox, SE Black… - Stroke, 2006 - Am Heart Assoc
In the above titled article, 1 the authors reviewed 7 published studies that compared cerebral
blood flow (CBF) measurements with a diagnostic gold standard (follow-up brain CT/MRI) …

Cerebral blood flow thresholds in acute stroke triage

MH Lev, RG Gonzalez, PW Schaefer, WJ Koroshetz… - Stroke, 2006 - Am Heart Assoc
We read with interest the recent article by Bandera and colleagues reporting their systematic
review of cerebral blood flow (CBF) thresholds for ischemic penumbra and infarct core in …

Response to Letters by Lee et al and Lev et al

N Latronico, M Botteri, E Bandera, C Minelli - Stroke, 2006 - Am Heart Assoc
Lee et al rightly raise the issue of CBF thresholds variability attributable to the different
measurement techniques used. We addressed this important problem in our review, and the …