SUMMARY 1 Photodynamic therapy is an established modality for the treatment of solid
tumours and other accessible lesions. Although the concept and practice of combining light …

Fluorescence intensity measurements have the potential to facilitate the diagnoses of many
pathological conditions. However, accurate interpretation of the measurements is …

The success of fluorescence experiments requires attention to experimental details and an
understanding of the instrumentation. There are also many potential artifacts that can distort …

Early identification of high-risk disease could greatly reduce both mortality and morbidity due
to oral cancer. We describe a simple handheld device that facilitates the direct visualization …

To complement a project towards the development of real-time optical biopsy for brain tissue
discrimination and surgical resection guidance, the optical properties of various brain …

A Multimode nonlinear optical imaging technique based on the combination of multichannel
mode and Lambda mode is developed to investigate human dermis. Our findings show that …

Autofluorescence of rabbit and human epithelial tissues were studied by using a depth-
resolved fluorescence spectroscopy system with multiple excitations. Keratinization was …

Background We characterize the application of multiphoton microscopy to the observation of
the extracellular matrix of fresh unstained vessels. Method Combined two‐photon‐excited …

Neuropathology frozen section diagnoses are difficult in part because of the small tissue
samples and the paucity of adjunctive rapid intraoperative stains. This study aims to explore …

purpose. Choroidal neovascularization (CNV) is the end point of several ocular diseases
that lead to blindness. The authors developed an imaging technique for visualizing and …