Oxidant and antioxidant balance in the airways and airway diseases

I Rahman, SK Biswas, A Kode - European journal of pharmacology, 2006 - Elsevier
Although oxygen is a prerequisite to life, at concentrations beyond the physiological limits it
may be hazardous to the cells. Since the lungs are directly exposed to very high amounts of …

Nrf2 defends the lung from oxidative stress

HY Cho, SP Reddy, SR Kleeberger - Antioxidants & redox signaling, 2006 - liebertpub.com
Nuclear factor, erythroid 2 related factor 2 (Nrf2) belongs to the Cap'n'collar/basic region
leucine zipper (CNC-bZIP) transcription factor family, and is activated by diverse oxidants …

Peroxynitrite induces HO-1 expression via PI3K/Akt-dependent activation of NF-E2-related factor 2 in PC12 cells

MH Li, YN Cha, YJ Surh - Free Radical Biology and Medicine, 2006 - Elsevier
Peroxynitrite is a strong oxidant produced by rapid interaction between superoxide anion
and nitric oxide radicals and induces oxidative stress and cell death. Treatment of PC12 …

Heme oxygenase-1 mediates the anti-inflammatory effects of acute alcohol on IL-10 induction involving p38 MAPK activation in monocytes

Y Drechsler, A Dolganiuc, O Norkina… - The Journal of …, 2006 - journals.aai.org
Inflammation and immunoregulatory cytokines play a central role in alcohol-induced liver
damage. We previously reported that acute alcohol treatment augments IL-10 and inhibits …

Lung injury and recovery after exposure to blast overpressure

M Chavko, WK Prusaczyk… - Journal of Trauma and …, 2006 - journals.lww.com
Background: A critical immediate determinant of survival after exposure to blast
overpressure (BOP) is pulmonary damage, but mechanisms of injury and the course of …

Differential gene expression of NADPH oxidase (p22phox) and hemoxygenase‐1 in patients with Type 2 diabetes and microangiopathy

A Adaikalakoteswari, M Balasubramanyam… - Diabetic …, 2006 - Wiley Online Library
Aims While the downstream effects of increased reactive oxygen species (ROS) in the
pathogenesis of diabetes were well studied, only a few studies have explored the cellular …

Expression of heme oxygenase-1 in the lungs of rats exposed to crystalline silica

H Nagatomo, Y Morimoto, T Oyabu… - Journal of …, 2006 - academic.oup.com
Abstract Expression of Heme Oxygenase-1 in the Lungs of Rats Exposed to Crystalline
Silica: Hiroko Nagatomo, et al. Department of Occupational Pneumology, Institute of …

Kohlenmonoxid: toxisches Molekül mit antiinflammatorischen und zytoprotektiven Eigenschaften

P Schober, A Koch, K Zacharowski… - AINS-Anästhesiologie …, 2006 - thieme-connect.com
Kohlenmonoxid entsteht bei inkompletter Verbrennung organischer Materie, wird über die
Lungen in den Kreislauf aufgenommen und verdrängt dort Sauerstoff aus der …

[PDF][PDF] Einfluss von endogenem NO auf die Expression von HO-1-mRNA in der Rattenleber

A Welle - 2006 - freidok.uni-freiburg.de
Seit das Enzym Hämoxygenase von Tenhunen et al. Ende der 60er Jahre erstmals als
Hämspaltendes Enzym beschrieben wurde, hat die Forschung auf diesem Gebiet große …

[引用][C] IGF-1 保护高氧性肺损伤作用机制的研究近况

黄月艳, 李强 - 右江民族医学院学报, 2006