CYP1A in TCDD toxicity and in physiology–with particular reference to CYP dependent arachidonic acid metabolism and other endogenous substrates
AB Rifkind - Drug metabolism reviews, 2006 - Taylor & Francis
Toxicologic and physiologic roles of CYP1A enzyme induction, the major biochemical effect
of aryl hydrocarbon receptor activation by TCDD and other receptor ligands, are unknown …
of aryl hydrocarbon receptor activation by TCDD and other receptor ligands, are unknown …
Developmental toxicity of 4-ring polycyclic aromatic hydrocarbons in zebrafish is differentially dependent on AH receptor isoforms and hepatic cytochrome P4501A …
Polycyclic aromatic hydrocarbons (PAHs) derived from fossil fuels are ubiquitous
contaminants and occur in aquatic habitats as highly variable and complex mixtures of …
contaminants and occur in aquatic habitats as highly variable and complex mixtures of …
Zebrafish as a model for developmental neurotoxicity testing
C Ton, Y Lin, C Willett - Birth Defects Research Part A: Clinical …, 2006 - Wiley Online Library
BACKGROUND: To establish zebrafish as a developmental toxicity model, we used 7 well‐
characterized compounds to examine several parameters of neurotoxicity during …
characterized compounds to examine several parameters of neurotoxicity during …
Uncoupling of cytochrome P450 1A and stimulation of reactive oxygen species production by co-planar polychlorinated biphenyl congeners
JJ Schlezinger, WDJ Struntz, JV Goldstone… - Aquatic toxicology, 2006 - Elsevier
The non-ortho-polychlorinated biphenyl (PCB) congener 3, 3′ 4, 4′-tetrachlorobiphenyl
(PCB 77) can uncouple the catalytic cycle of fish (scup) cytochrome P4501A (CYP1A) and …
(PCB 77) can uncouple the catalytic cycle of fish (scup) cytochrome P4501A (CYP1A) and …
Molecular Mechanisms of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Cardiovascular Embryotoxicity
HMH Goldstone, JJ Stegeman - Drug Metabolism Reviews, 2006 - Taylor & Francis
2, 3, 7, 8 Tetrachlorodibenzo-p-dioxin (TCDD) and related planar halogenated aromatic
hydrocarbons are widespread environmental contaminants and potent developmental …
hydrocarbons are widespread environmental contaminants and potent developmental …
Toxic effects of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) in developing red seabream (Pagrus major) embryo: an association of morphological deformities with …
The toxicity of dioxins such as 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) is mainly
mediated by the aryl hydrocarbon receptor (AHR), which regulates the multiple target genes …
mediated by the aryl hydrocarbon receptor (AHR), which regulates the multiple target genes …
CYP1A Induction and Blue Sac Disease in Early Life Stages of White Suckers (Catostomus commersoni) Exposed to Oil Sands
MV Colavecchia, PV Hodson… - Journal of Toxicology and …, 2006 - Taylor & Francis
The objectives of this study were to evaluate the influence of natural oil sands on the early
developmental stages of white sucker (Catostomus commersoni) and to determine whether …
developmental stages of white sucker (Catostomus commersoni) and to determine whether …
[PDF][PDF] Fish embryo toxicity assays
T Braunbeck, E Lammer - Ger. Fed. Environ. Agency, 2006 - researchgate.net
1.0 Executive summary This document provides information about embryo toxicity tests
conducted in different fish species. The review has been designed as a source of …
conducted in different fish species. The review has been designed as a source of …
670 nanometer light treatment attenuates dioxin toxicity in the developing chick embryo
RL Yeager, J Lim, DS Millsap… - … of Biochemical and …, 2006 - Wiley Online Library
Abstract 2, 3, 7, 8‐Tetrachlorodibenzo‐p‐dioxin (TCDD) is an acutely toxic anthropogenic
chemical. Treatment with a red to near‐infrared (630–1000 nm) light‐emitting diode (LED) …
chemical. Treatment with a red to near‐infrared (630–1000 nm) light‐emitting diode (LED) …
Age structure and growth of Semotilus atromaculatus(Mitchill) in PCB‐contaminated streams
DS Henshel, DW Sparks, TP Simon… - Journal of Fish …, 2006 - Wiley Online Library
Creek chub Semotilus atromaculatus from two PCB contaminated streams (Clear Creek and
Richland Creek) at three locations and a reference stream (Little Indian Creek), Indiana …
Richland Creek) at three locations and a reference stream (Little Indian Creek), Indiana …