Imparting size, shape, and composition control of materials for nanomedicine
LE Euliss, JA DuPont, S Gratton… - Chemical Society …, 2006 - pubs.rsc.org
This tutorial review presents an overview of strategies for the synthesis and fabrication of
organic nanomaterials, specifically those with potential for use in medical applications …
organic nanomaterials, specifically those with potential for use in medical applications …
Nanostructured devices based on block copolymer assemblies for drug delivery: designing structures for enhanced drug function
N Nishiyama, K Kataoka - Polymer Therapeutics II, 2006 - Springer
Block copolymers spontaneously assemble into nanoscaled polymeric micelles, which have
significant potential as drug carriers. Following much work in related fields over the last …
significant potential as drug carriers. Following much work in related fields over the last …
Block copolymer micelles as delivery vehicles of hydrophobic drugs: micelle–cell interactions
R Savić, A Eisenberg, D Maysinger - Journal of drug targeting, 2006 - Taylor & Francis
One-third of drugs in development are water insoluble and one-half fail in trials because of
poor pharmacokinetics. Block copolymer micelles are nanosized particles that can solubilize …
poor pharmacokinetics. Block copolymer micelles are nanosized particles that can solubilize …
Anticancer efficacies of cisplatin-releasing pH-responsive nanoparticles
P Xu, EA Van Kirk, WJ Murdoch, Y Zhan… - …, 2006 - ACS Publications
The objective of these investigations was to test the hypothesis that a rapid cytoplasmic
release profile from nanoparticles would potentiate the anticancer activity of cisplatin …
release profile from nanoparticles would potentiate the anticancer activity of cisplatin …
Highly stable core-surface-crosslinked nanoparticles as cisplatin carriers for cancer chemotherapy
Cisplatin is a potent anticancer drug with low solubility in water. A new type of highly stable
polymer micelles, namely core-surface-crosslinked nanoparticles (SCNPs) made from …
polymer micelles, namely core-surface-crosslinked nanoparticles (SCNPs) made from …
Using the reversible addition–fragmentation chain transfer process to synthesize core‐crosslinked micelles
L Zhang, K Katapodi, TP Davis… - Journal of Polymer …, 2006 - Wiley Online Library
Abstract Poly (2‐hydroxyethyl acrylate)–poly (n‐butyl acrylate) block copolymers were
synthesized with the reversible addition–fragmentation chain transfer (RAFT) process. The …
synthesized with the reversible addition–fragmentation chain transfer (RAFT) process. The …
Micellization Temperature and Pressure for Polystyrene-block-polyisoprene in Subcritical and Supercritical Propane
Polystyrene-block-polyisoprene forms micelles in supercritical and subcritical propane upon
cooling and decompression. These micelles decompose upon heating and compression. At …
cooling and decompression. These micelles decompose upon heating and compression. At …