The treatment of hepatitis C has dramatically improved over the past decade. Unlike any
other chronic viral infection, a significant proportion of patients with chronic hepatitis C can …

Obligate intracellular parasites such as the hepatitis C virus (HCV) have to cope intensively
with immune responses in order to establish persistent infection. Powerful antiviral …

Three percent of the world's population is chronically infected with the hepatitis C virus
(HCV) and at risk of developing liver cancer. Effective cellular immune responses are …

IFN-γ is known as the initial and primary inducer of immunoproteasomes during viral
infections. We now report that type I IFN induced the transcription and translation of …

CD4+ T cells are thought to contribute to antiviral immune responses by secretion of
cytokines thereby providing help to CD8+ T and B cells. However, perforin‐positive cytotoxic …

Prior studies have suggested that natural killer (NK) cell function might be impaired in
chronic hepatitis C virus (HCV) infection. Circulating NK cell frequency and cytolytic activity …

This EASL monothematic conference aimed to review in a 2-day meeting the most recent
aspects of liver transplantation for viral hepatitis. Experts from Europe and overseas …

As interferon/ribavirin-based standard therapy is curative in only about half of HCV patients,
there remains an important need for alternatives including vaccines. The novel peptide …

Abstract Interleukin‐7 (IL‐7) is required for the establishment and maintenance of memory
CD4+ and CD8+ T lymphocytes, and cells lacking IL‐7Rα (CD127) demonstrate impaired IL …

CD8 T cell killing of hepatitis C virus (HCV)‐infected hepatocytes is thought to contribute to
liver damage during chronic HCV infection, whereas the participation of HCV‐nonspecific …