CuI‐catalyzed alkyne–azide cycloaddition provides 1, 4‐disubstituted 1, 2, 3‐triazoles with
such efficiency and scope that the transformation has been described as “click” chemistry …

The fixation of ligands onto molecules, surfaces and materials by use of reactions using a
simple and unified chemistry is among the everlasting desires of chemists. Besides the …

Multifunctionalized dihydropyrimidine-5-carboxylic amides and esters are generated in a
multistep sequence integrating a variety of enabling and high throughput technologies such …

A practical access to alkyl-and aryl-substituted (E)-2-(azidomethyl) alkenoates and related
azido compounds from the corresponding allylic bromides in aqueous acetone is described …

Multicomponent reactions offer convenient procedures for the introduction of many points of
structural diversity into heterocyclic compounds prepared in a straightforward manner in a …

A second generation focused library of 30 tetrahydropyrimidinone amides was prepared.
The design was based on the structure of an Hsp70 modulator. This small library …

Controlled microwave heating has found many important applications in the synthesis of
heterocycles. Almost all kinds of heterocycles have been prepared (or their preparation …

Combinatorial methodologies have dramatically changed the chemical research and
discovery process, offering an unlimited source of new molecule entities to be screened for …

RESUMEN La Química Verde tiene como meta proteger el ambiente mediante el desarrollo
de nuevas metodologías no contaminantes; en este sentido la sonoquímica es un área que …