Huntington Disease (HD) is characterized by choreic involuntary movements and striatal
vulnerability. A2A receptors expressed on GABAergic striatal neurons have been suggested …

In vivo microdialysis in C57BL/6J (B6) mouse was used to test the hypothesis that activating
adenosine A2A receptors in the pontine reticular formation (PRF) increases acetylcholine …

Endogenous adenosine acting at the adenosine A2A receptor (A2AR) can modify brain
injury in a variety of neurological disorder models. However, both A2AR activation and …

Abstract Adenosine A1 and A2A receptors mediate distinct cardiovascular components of
defense reactions that are ascribed, in part, to opposing actions within the nucleus tractus …

Previous studies have shown that cortical stimulation selectively activates extracellular
signal-regulated kinase 1/2 (ERK1/2) phosphorylation and immediate early gene expression …

The aim of the present paper was to examine, in a comparative way, the occurrence and the
mechanisms of the interactions between adenosine A 2A receptors (A 2A Rs) and …

Although still a disorder of unknown etiology, Parkinson's disease (PD) has provided a
number of clues that have led to clinical trials of neuroprotection. For example, defects in …

In the striatum, adenosine A 2A and dopamine D 2 receptors exert reciprocal antagonistic
interactions that modulate the function of GABAergic enkephalinergic neurons. We have …

The molecular mechanisms involved in the reversion of levodopa‐induced motor
fluctuations by the adenosine A2A antagonist 8‐(3‐chlorostryryl) caffeine (CSC) were …

A series of 15 experiments was conducted to investigate functional interactions between
dopamine D 2 and adenosine A 2A receptors in rat models of parkinsonism, in which the …