Silks are naturally occurring polymers that have been used clinically as sutures for centuries.
When naturally extruded from insects or worms, silk is composed of a filament core protein …

Bone is the most implanted tissue after blood. The major solid components of human bone
are collagen (a natural polymer, also found in skin and tendons) and a substituted …

Bone auto-and allografts have inherent drawbacks, therefore the treatment of non-unions
and critical size defects in load bearing long bones would benefit from the use of …

Tissue and organ replacement have quickly outpaced available supply. Tissue
bioengineering holds the promise for additional tissue availability. Various scaffolds are …

Drug delivery to the peritoneum is hampered by rapid clearance, and could be improved by
application of controlled release technology. We investigated the suitability for peritoneal …

Silk fibroin scaffolds were studied as a new biomaterial option for tissue-engineered
cartilage-like tissue. Human bone marrow–derived mesenchymal stem cells (MSCs) were …

In this paper, we report on engineering 3-D pulmonary tissue constructs in vitro. Primary
isolates of murine embryonic day 18 fetal pulmonary cells (FPC) were comprised of a mixed …

Silk fibroin is an important polymer for scaffold designs, forming biocompatible and
mechanically robust biomaterials for bone, cartilage, and ligament tissue engineering. In the …

An ideal 3D-scaffold for tissue regeneration should have similarity to native ECM in terms of
both chemical composition and physical nanostructure. Recently, nanostructured …

The use of biodegradable microcarriers as initial supports for tissue engineering has been
demonstrated to be advantageous for maintaining a differentiated cell phenotype; the high …