Encapsulated gas microbubbles are well known as ultrasound contrast agents for medical
ultrasound imaging. Nonetheless, not only do these microbubbles help to image, but they …

Drug development is a long process that generally spans about 10 to 15 years. The shift in
recent drug discovery to novel agents against specific molecular targets highlights the need …

Ultrasound contrast microbubbles have the ability to enhance endothelial cell permeability
and thus may be used as a new way to deliver drugs. It facilitates the transfer of extracellular …

This study describes a method of gene delivery to pancreatic islets of adult, living animals by
ultrasound targeted microbubble destruction (UTMD). The technique involves incorporation …

In the present study, we addressed the interactions among ultrasound, microbubbles, and
living cells as well as consequent arising bioeffects. We specifically investigated whether …

purpose. The cornea is an ideal organ for evaluating gene transfer because it can be treated
noninvasively and monitored easily. The present study was performed to investigate the …

Ultrasound, which has been conventionally used for diagnostics until recently, is now being
extensively used for drug and gene delivery. This transformation has come about primarily …

Therapeutic ultrasound (TUS) has the potential of becoming a powerful nonviral method for
the delivery of genes into cells and tissues. Understanding the mechanism by which TUS …

Determining the rupture pressure threshold of ultrasound contrast agent microbubbles has
significant applications for contrast imaging, development of therapeutic agents, and …

Acoustic cavitation takes place when tiny gas bubbles oscillate, grow, and collapse in liquid
under the influence of ultrasonic field. This study reviews cavitation bioeffects that are found …