It has been demonstrated that nuclear lamins are important proteins in maintaining cellular
as well as nuclear integrity, and in maintaining chromatin organization in the nucleus …

Hemidesmosomes are multiprotein adhesion complexes that promote epithelial stromal
attachment in stratified and complex epithelia. Modulation of their function is of crucial …

Nuclear migration and positioning within cells are critical for many developmental processes
and are governed by the cytoskeletal network. Although mechanisms of nuclear-cytoskeletal …

Emerin is a type II inner nuclear membrane (INM) protein of unknown function. Emerin
function is likely to be important because, when it is mutated, emerin promotes both skeletal …

The novel SUN-domain family of nuclear envelope proteins interacts with various KASH-
domain partners to form SUN-domain-dependent'bridges' across the inner and outer nuclear …

UNC-84 is required to localize UNC-83 to the nuclear envelope where it functions during
nuclear migration. A KASH domain in UNC-83 was identified. KASH domains are conserved …

The nucleus in eukaryotic cells can move within the cytoplasm, and its position is crucial for
many cellular events, including migration and differentiation. Nuclear anchorage and …

Lamins form structural filaments in the nucleus. Mutations in A-type lamins cause muscular
dystrophy, cardiomyopathy and other diseases, including progeroid syndromes. To identify …

Emery-Dreifuss muscular dystrophy is an inherited muscular disorder clinically
characterized by slowly progressive weakness affecting humero-peroneal muscles, early …

X‐linked Emery‐Dreifuss muscular dystrophy (X‐EDMD) is inherited through mutations in
EMD, which encodes a nuclear membrane protein named emerin. Emerin is expressed in …