It now appears that, in most obese patients, obesity is associated with a low-grade
inflammation of white adipose tissue (WAT) resulting from chronic activation of the innate …

Leptin is a versatile 16 kDa peptide hormone, with a tertiary structure resembling that of
members of the long-chain helical cytokine family. It is mainly produced by adipocytes in …

Obesity is a major health problem and a risk factor for type 2 diabetes. Leptin, an adipocyte-
secreted hormone, acts on the hypothalamus to inhibit food intake and increase energy …

Population‐based studies have shown strong relationship between inflammatory markers
and metabolic disturbances, obesity, and atherosclerosis, whereas inflammation has been …

Aims/hypothesis The aim of this study was to confirm a link between mitochondrial
dysfunction and type 2 diabetes. Materials and methods Cellular levels of mitochondrial …

Obesity is a major risk factor for heart disease. In the face of obesity's growing prevalence, it
is important for physicians to be aware of emerging research of novel mechanisms through …

Leptin and insulin are key hormones involved in the regulation of energy balance and
glucose homeostasis. Development of resistance to the action of these hormones, which can …

The mechanisms underlying leptin resistance are still being defined. We report here the
presence in human blood of several serum leptin-interacting proteins (SLIPs), isolated by …

Leptin, which was identified originally as an adipocyte-derived protein, was regarded for
years as an exclusive regulator of satiety and energy homeostasis. A role for leptin in …

In recent years, the number of researchers interested in mammary development and
mammary function in dairy animals has declined. More importantly this cadre of workers has …