The imprinted gene cluster at the telomeric end of mouse chromosome 7 contains a
differentially methylated CpG island, KvDMR, that is required for the imprinting of multiple …

In mammals, some genes categorized as imprinted genes are exclusively expressed either
from maternal or paternal allele. This parental‐origin‐specific gene expression is regulated …

The epigenetic phenomenon of genomic imprinting provides an additional level of gene
regulation that is confined to a limited number of genes, frequently, but not exclusively …

Expression of the Air ncRNA is necessary to silence multiple genes in cis in the imprinted
Igf2r cluster. However, its mode of action is unknown. Here, we characterize co‐and post …

Leptin is a fat hormone regulating energy homeostasis. Here, it is reported that the promoter
and CpG island of the autosomal gene Leptin (LEP) is a tissue-specific differentially …

DNA methylation is a major epigenetic mechanism that has been suggested to control
developmental gene regulation during embryogenesis, but its regulatory mechanisms …

Findings from recent studies have suggested that the low survival rate of animals derived via
somatic cell nuclear transfer (SCNT) may be in part due to epigenetic abnormalities brought …

Imprinted genes in mammals show monoallelic expression dependent on parental origin
and are often associated with differentially methylated regions (DMRs). There are two …

Cell surface mannose 6-phosphate/insulin-like growth factor II receptors (M6P/IGF2R) bind
and target exogenous insulin-like growth factor II (IGF2) to the prelysosomes where it is …

Phylogenetic comparison of extant mammals with divergent imprint status is a powerful
method for identifying critical components of imprint regulation at individual loci. The entire …