Clinical consequences of red cell storage in the critically ill

A Tinmouth, D Fergusson, IC Yee, PC Hébert… - …, 2006 - Wiley Online Library
Red cell (RBC) transfusions are a potentially life‐saving therapy employed during the care
of many critically ill patients to replace losses in hemoglobin to maintain oxygen delivery to …

Key issues in advanced bleeding care in trauma

R Rossaint, V Cerny, TJ Coats, J Duranteau… - Shock, 2006 - journals.lww.com
The incidence of hemostatic abnormalities in the early hours after traumatic incident is high
and represents an independent predictor of mortality. Key factors in the development of …

Red blood cell transfusions and nosocomial infections in critically ill patients

RW Taylor, J O'Brien, SJ Trottier… - Critical care …, 2006 - journals.lww.com
Objective: A previous retrospective evaluation of Project Impact data demonstrated an
association between red blood cell transfusions, nosocomial infections, and poorer …

Recommendations on the use of recombinant activated factor VII as an adjunctive treatment for massive bleeding–a European perspective

JL Vincent, R Rossaint, B Riou, Y Ozier, D Zideman… - Critical Care, 2006 - Springer
Introduction Our aim was to develop consensus guidelines for use of recombinant activated
factor VII (rFVIIa) in massive hemorrhage. Methods A guidelines committee derived the …

Nonoperative management of splenic injuries: improved results with angioembolization

C Gaarder, JB Dormagen, T Eken… - Journal of Trauma …, 2006 - journals.lww.com
Background: Nonoperative management (NOM) of patients with severe splenic injuries
carries a significant risk of failure. We hypothesized that adding angiographic embolization …

Recombinant factor VIIa in patients with coagulopathy secondary to anticoagulant therapy, cirrhosis, or severe traumatic injury: review of safety profile

JH Levy, A Fingerhut, T Brott, IH Langbakke… - …, 2006 - Wiley Online Library
BACKGROUND: In recent years, the hemostatic agent recombinant factor VIIa (rFVIIa) has
emerged as a potentially new therapeutic agent for management of coagulopathy in patients …

Blood transfusion is associated with infection and increased resource utilization in combat casualties

JR Dunne, MS Riddle, J Danko… - The American …, 2006 - journals.sagepub.com
Combat casualty care has made significant advances in recent years, including
administration of blood products in far-forward locations. However, recent studies have …

Blood transfusion in critically injured patients: a prospective study

E Beale, J Zhu, L Chan, I Shulman, R Harwood… - Injury, 2006 - Elsevier
BACKGROUND: Despite evolving evidence that transfusion risks outweigh benefits in some
patients, the critically injured continue to receive large quantities of blood. The present study …

Critical care issues in the early management of severe trauma

A Garcia - Surgical Clinics, 2006 - surgical.theclinics.com
Violent trauma and road traffic injuries kill more than 2.5 million people in the world every
year. It has been calculated by the World Health Organization that in 2002 there occurred …

Cumulative risks of early red blood cell transfusion

L Napolitano - Journal of Trauma and Acute Care Surgery, 2006 - journals.lww.com
Blood transfusion in trauma has been identified as an independent predictor of multiple
organ failure (MOF), systemic inflammatory response syndrome (SIRS), increased post …