Enhancing the circulating half-life of antibody-based fusion proteins
SD Gillies, C Burger, KM Lo - US Patent 7,091,321, 2006 - Google Patents
US7091321B2 - Enhancing the circulating half-life of antibody-based fusion proteins - Google
Patents US7091321B2 - Enhancing the circulating half-life of antibody-based fusion proteins …
Patents US7091321B2 - Enhancing the circulating half-life of antibody-based fusion proteins …
Expression technology for proteins containing a hybrid isotype antibody moiety
SD Gillies, KM Lo - US Patent 7,148,321, 2006 - Google Patents
Disclosed are methods and compositions for efficiently expressing antibody fusion proteins.
Antibody fusion pro teins of the invention include a hybrid antibody moiety containing …
Antibody fusion pro teins of the invention include a hybrid antibody moiety containing …
Reducing the immunogenicity of fusion proteins
SD Gillies, AA Hamilton - US Patent 6,992,174, 2006 - Google Patents
4,196,265 A 4/1980 Koprowski et al. 4,469,797 A 9/1984 Albarella 4,522,811 A 6/1985
Eppstein et al. 4,667,016 A 5/1987 Lai et al. 4,676.980 A 6/1987 Segal et al. 4,703,008 A …
Eppstein et al. 4,667,016 A 5/1987 Lai et al. 4,676.980 A 6/1987 Segal et al. 4,703,008 A …
Multiple cytokine protein complexes
SD Gillies, KM Lo - US Patent 7,141,651, 2006 - Google Patents
The invention relates to protein complexes and fusion proteins including at least two
different cytokine molecules. The protein complexes and fusion proteins may further include …
different cytokine molecules. The protein complexes and fusion proteins may further include …
Dosages for treatment with anti-EGFR antibodies
S Baughman, S Shak - US Patent App. 11/443,943, 2006 - Google Patents
US20060210561A1 - Dosages for treatment with anti-EGFR antibodies - Google Patents
US20060210561A1 - Dosages for treatment with anti-EGFR antibodies - Google Patents …
US20060210561A1 - Dosages for treatment with anti-EGFR antibodies - Google Patents …
Treatment of bone disorders
J Quan, K Sewell - US Patent App. 11/363,091, 2006 - Google Patents
Methods of treatment of various bone indications, such as osteoporosis, in a mammal are
provided Wherein an effective amount of an antagonist that binds to a B-cell surface marker …
provided Wherein an effective amount of an antagonist that binds to a B-cell surface marker …
Methods for identifying tumors responsive to treatment with HER dimerization inhibitors (HDIs)
M Sliwkowski, D Eberhard - US Patent App. 11/370,304, 2006 - Google Patents
Tumors are identified as responsive to treatment with HER dimerization inhibitors (HDIs) are
identified by treating a HER expressing tumor with an HDI (which may be the same or …
identified by treating a HER expressing tumor with an HDI (which may be the same or …
Expression technology for proteins containing a hybrid isotype antibody moiety
S Gillies, J Way, KM Lo - US Patent App. 11/489,653, 2006 - Google Patents
Disclosed are methods and compositions for efficiently expressing antibody fusion proteins.
Antibody fusion pro teins of the invention include a hybrid antibody moiety containing …
Antibody fusion pro teins of the invention include a hybrid antibody moiety containing …
Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens
SD Gillies, KM Lo, JS Wesolowski Jr - US Patent 7,067,110, 2006 - Google Patents
5,514,582 A 5/1996 Capon et al. fusing the preselected antigen to an immunoglobulin heavy
5,538,866 A* 7/1996 Israeli et al. chain constant region to produce an Fc-antigen fusion pro …
5,538,866 A* 7/1996 Israeli et al. chain constant region to produce an Fc-antigen fusion pro …
Identification of polynucleotides and polypetide for predicting activity of compounds that interact with protein tyrosine kinase and or protein tyrosine kinase pathways
F Huang, C Fairchild, F Lee, P Shaw - US Patent App. 10/501,035, 2006 - Google Patents
The present invention describes polynucleotides and polypeptides that have been
discovered to correlate to the relative intrinsic Sensitivity or resistance of cells, eg, colon cell …
discovered to correlate to the relative intrinsic Sensitivity or resistance of cells, eg, colon cell …