Asthma: defining of the persistent adult phenotypes
SE Wenzel - The Lancet, 2006 - thelancet.com
The common disease asthma is probably not a single disease, but rather a complex of
multiple, separate syndromes that overlap. Although clinicians have recognised these …
multiple, separate syndromes that overlap. Although clinicians have recognised these …
Overview of the pharmacogenetics of asthma treatment
Asthma affects approximately 300 million individuals worldwide. Medications comprise a
substantial portion of asthma expenditures. Despite the availability of three primary …
substantial portion of asthma expenditures. Despite the availability of three primary …
Increased glucocorticoid receptor β alters steroid response in glucocorticoid-insensitive asthma
E Goleva, L Li, PT Eves, MJ Strand… - American journal of …, 2006 - atsjournals.org
Rationale: Glucocorticoids (GCs) are highly effective in the treatment of asthma. However,
some individuals have GC-insensitive asthma. Objectives: To evaluate the functional …
some individuals have GC-insensitive asthma. Objectives: To evaluate the functional …
Response profiles to fluticasone and montelukast in mild-to-moderate persistent childhood asthma
RS Zeiger, SJ Szefler, BR Phillips, M Schatz… - Journal of Allergy and …, 2006 - Elsevier
BACKGROUND: Outcome data are needed to base recommendations for controller asthma
medication use in school-aged children. OBJECTIVE: We sought to determine …
medication use in school-aged children. OBJECTIVE: We sought to determine …
Features of severe asthma in school-age children: atopy and increased exhaled nitric oxide
AM Fitzpatrick, BM Gaston, SC Erzurum… - Journal of Allergy and …, 2006 - Elsevier
BACKGROUND: Children with severe asthma have persistent symptoms despite treatment
with inhaled corticosteroids (ICSs). The differentiating features of severe asthma in children …
with inhaled corticosteroids (ICSs). The differentiating features of severe asthma in children …
Leitlinie zur Diagnostik und Therapie von Patienten mit Asthma
R Buhl, D Berdel, CP Criée, A Gillissen, P Kardos… - …, 2006 - thieme-connect.com
Neue Erkenntnisse in der Diagnostik und Therapie des Asthmas machen eine Neufassung
der Empfehlungen der Deutschen Atemwegsliga zur Asthma− Behandlung notwendig. So …
der Empfehlungen der Deutschen Atemwegsliga zur Asthma− Behandlung notwendig. So …
Role of spirometry and exhaled nitric oxide to predict exacerbations in treated asthmatics
AF Gelb, CF Taylor, CM Shinar, C Gutierrez, N Zamel - Chest, 2006 - Elsevier
Objective To evaluate the complementary roles of exhaled nitric oxide (NO) and spirometry
to predict asthma exacerbations requiring one or more tapering courses of systemic …
to predict asthma exacerbations requiring one or more tapering courses of systemic …
Low sputum eosinophils predict the lack of response to beclomethasone in symptomatic asthmatic patients
E Bacci, S Cianchetti, ML Bartoli, FL Dente, A Di Franco… - Chest, 2006 - Elsevier
Background: The prognostic role of low sputum eosinophils in steroid-naïve, symptomatic
asthmatic patients is controversial. Aim: To verify whether low sputum eosinophils predict …
asthmatic patients is controversial. Aim: To verify whether low sputum eosinophils predict …
Bronchodilation and bronchoconstriction: predictors of future lung function in childhood asthma
KG Tantisira, AL Fuhlbrigge, J Tonascia… - Journal of Allergy and …, 2006 - Elsevier
BACKGROUND: Persistently low levels of lung function are associated with subsequent
symptoms in patients with asthma as children. OBJECTIVES: We hypothesized that objective …
symptoms in patients with asthma as children. OBJECTIVES: We hypothesized that objective …
Peroxisome proliferator‐activated receptor‐γ agonists as potential anti‐inflammatory agents in asthma and chronic obstructive pulmonary disease
M Spears, C McSharry… - Clinical & Experimental …, 2006 - Wiley Online Library
Inhaled corticosteroids are the most effective therapy for chronic persistent asthma and have
a role in the treatment of chronic obstructive pulmonary disease (COPD). However …
a role in the treatment of chronic obstructive pulmonary disease (COPD). However …