Phase III trial of fluorouracil-based chemotherapy regimens plus radiotherapy in postoperative adjuvant rectal cancer: GI INT 0144

SR Smalley, JK Benedetti, SK Williamson… - Journal of clinical …, 2006 - ascopubs.org
Purpose Adjuvant chemoradiotherapy after or before resection of high-risk rectal cancer
improves overall survival (OS) and pelvic control. We studied three postoperative …

Can pelvic radiotherapy be omitted in select patients with rectal cancer?

LL Lai, CD Fuller, LA Kachnic, CR Thomas Jr - Seminars in oncology, 2006 - Elsevier
Randomized prospective trials have shown the benefits of adjuvant radiotherapy in
decreasing local recurrence rates in stage II and stage III rectal cancer. However, some …

Adjuvant chemotherapy with uracil–tegafur for pathological stage III rectal cancer after mesorectal excision with selective lateral pelvic lymphadenectomy: a …

T Akasu, Y Moriya, Y Ohashi, S Yoshida… - Japanese journal of …, 2006 - academic.oup.com
Background: Although adjuvant radiotherapy was proved to be effective for local control of
rectal cancer even after standardized mesorectal excision, the role of adjuvant …

[HTML][HTML] Alternative clinical end points in rectal cancer—are we getting closer?

R Glynne-Jones, S Mawdsley, T Pearce, M Buyse - Annals of oncology, 2006 - Elsevier
Background: In rectal cancer a high risk of local recurrence has been reported for patients
treated by surgery alone. It is also recognised that 20%–40% of rectal cancer patients …

Rectal cancer surgery in the elderly: a multivariate analysis of outcome risk factors

A Bufalari, G Giustozzi, MF Burattini… - Journal of surgical …, 2006 - Wiley Online Library
Abstract Background and Objectives Geriatric population life expectancy is rapidly
increasing and the impact of major surgical procedures is not well defined. The purpose of …

Effect of timing of surgery on survival after preoperative hyperfractionated accelerated radiotherapy (HART) for locally advanced rectal cancer (LARC): is it a matter of …

PA Coucke, M Notter, M Matter, F Fasolini… - Acta …, 2006 - Taylor & Francis
We intend to analyse retrospectively whether the time interval (“gap duration”= GD) between
preoperative radiotherapy and surgery in locally advanced rectal cancer (LARC) has an …

CPT-11 and concomitant hyperfractionated accelerated radiotherapy induce efficient local control in rectal cancer patients: results from a phase II

V Voelter, A Zouhair, H Vuilleumier, M Matter… - British journal of …, 2006 - nature.com
Patients with rectal cancer are at high risk of disease recurrence despite neoadjuvant
radiochemotherapy with 5-Fluorouracil (5FU), a regimen that is now widely applied. In order …

Adjuvant chemotherapy with folinic acid and 5-fluorouracil in patients with locally advanced rectal cancer previously treated by preoperative radiochemotherapy and …

B Hildebrandt, B Rau, J Löffel, P Wust… - International journal of …, 2006 - Springer
Background and aims The role of postoperative adjuvant chemotherapy in patients with
rectal cancer pretreated by preoperative radiochemotherapy (RCT) and curative surgery is …

Evaluation of a protocol-based management of rectal cancer

KK Sasapu, D Sebag-Montefiore, AG Chalmers… - Diseases of the colon & …, 2006 - Springer
Introduction The management of rectal cancer is multidisciplinary. We have devised and
implemented a standardized protocol. This study was designed to evaluate the protocol and …

Adjuvant radiotherapy for rectal cancer

KT Moesta, F Köckerling - Journal of British Surgery, 2006 - academic.oup.com
Adjuvant radiotherapy for rectal cancer | British Journal of Surgery | Oxford Academic Skip
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