Kaposi's sarcoma-associated herpesvirus (KSHV) is the most recently discovered human
herpesvirus. It is the aetiological agent of Kaposi's sarcoma (KS), a tumour frequently …

The chemokine stromal cell–derived factor (SDF-1; also known as chemokine ligand 12
[CXCL12]) regulates many essential biological processes, including cardiac and neuronal …

Although combinations of drugs that target the HIV reverse transcriptase and protease
enzymes have clearly revolutionized the treatment of HIV/AIDS, problems with these agents …

Abstract Leukotropic human herpesvirus 6 (HHV-6) establishes a persistent infection
associated with inflammatory diseases and encodes chemokines that could chemoattract …

Numerous advances have been made recently that expand the understanding of Kaposi's
sarcoma pathogenesis. These findings and recent clinical trials of targeted therapy for …

Chemokines and their receptors play important roles in numerous physiological and
pathological processes. To develop natural chemokines into receptor probes and inhibitors …

Viral infections depend on an intimate relationship between the infectious agent and the
host cells. Viruses need the host cells for replication, while the innate-and adaptive …

US6989435B2 - Compounds and methods to inhibit or augment an inflammatory response -
Google Patents US6989435B2 - Compounds and methods to inhibit or augment an …

The extracellular part of transmembrane segment V (TM-V) is expected to be involved in the
activation process of 7TM receptors, but its role is far from clear. Here, we study the highly …

Pro‐inflammatory chemokines and their receptors exhibit elementary functions in cell
migration and in Th1‐driven inflammatory conditions. One therapeutic strategy to prevent …