Stem cells and tissue engineering: past, present, and future

JM Polak, AE Bishop - Annals of the New York Academy of …, 2006 - Wiley Online Library
Tissue engineering is an interdisciplinary field that brings together the principles of the life
sciences and medicine with those of engineering. The increase in its development over the …

Concise review: scientific and ethical roadblocks to human embryonic stem cell therapy

L Gruen, L Grabel - Stem cells, 2006 - academic.oup.com
Despite the identified therapeutic potential of embryonic stem cells for treating human
disease and injury, a number of roadblocks, scientific and ethical, stand in the way of …

Defined culture conditions of human embryonic stem cells

J Lu, R Hou, CJ Booth, SH Yang… - Proceedings of the …, 2006 - National Acad Sciences
Human embryonic stem cells (hESCs) are pluripotent cells that have the potential to
differentiate into any tissue in the human body; therefore, they are a valuable resource for …

A molecular scheme for improved characterization of human embryonic stem cell lines

R Josephson, G Sykes, Y Liu, C Ording, W Xu, X Zeng… - BMC biology, 2006 - Springer
Background Human embryonic stem cells (hESC) offer a renewable source of a wide range
of cell types for use in research and cell-based therapies to treat disease. Inspection of …

Using therapeutic cloning to fight human disease: a conundrum or reality?

VJ Hall, P Stojkovic, M Stojkovic - Stem cells, 2006 - academic.oup.com
The development and transplantation of autologous cells derived from nuclear transfer
embryonic stem cell (NT‐ESC) lines to treat patients suffering from disease has been termed …

Progress and prospects: gene transfer into embryonic stem cells

F Yates, GQ Daley - Gene therapy, 2006 - nature.com
With the isolation of human embryonic stem cells (hESCs) in 1998 came the realization of a
long-sought aspiration for an unlimited source of human tissue. The difficulty of …

Nonhuman sialic acid Neu5Gc is very low in human embryonic stem cell-derived neural precursors differentiated with B27/N2 and noggin: implications for …

IO Nasonkin, VE Koliatsos - Experimental neurology, 2006 - Elsevier
A concern recently has been raised that human embryonic stem cell (HESC) lines cultured
with currently available methods may have limited clinical usefulness due to the …

Estimating human embryonic stem-cell numbers

MS Rao, JM Auerbach - The Lancet, 2006 - thelancet.com
Craig Taylor and colleagues (Dec 10, p 2019) 1 estimate that about 150 human embryonic
stem-cell (hESC) lines would be needed for most of the UK population, and that as few as …

How many human embryonic stem cell lines are sufficient? A US perspective

CI Civin, MS Rao - Stem Cells, 2006 - academic.oup.com
Pluripotent human embryonic stem cells (hESCs), isolated from the inner cell mass of
preimplantation embryonic blastocysts, are able to self-renew and generate every human …

[PDF][PDF] Ethical legal and social issues in stem cell research and therapy

O Corrigan, K Liddell, J McMillan… - Cambridge Genetic …, 2006 - phgfoundation.org
Stem cell research is an important new domain of biomedical research that has the potential
to offer viable therapeutic options for debilitating disease and injury. However, stem cell …