It has been postulated that spatial working memory operates optimally within a limited range
of dopamine transmission and D1 dopamine receptor signaling in prefrontal cortex …

Dysfunction of central dopaminergic neurotransmission has been implicated in a series of
neuropsychiatric disorders, including Tourette's syndrome, schizophrenia, and drug and …

We imaged axons in layer (L) 1 of the mouse barrel cortex in vivo. Axons from thalamus and
L2/3/5, or L6 pyramidal cells were identified based on their distinct morphologies. Their …

Psychostimulant-induced alteration of dendritic spines on dopaminoceptive neurons in
nucleus accumbens (NAcc) has been hypothesized as an adaptive neuronal response that …

Addiction to cocaine is associated with persistent changes in synaptic function. The cycling
of actin between polymerized [F (for filamentous)] and depolymerized forms contributes to …

The hypothalamo–pituitary–adrenal (HPA) axis is the critical mediator of the vertebrate
stress response system, responding to environmental stressors by maintaining internal …

The potential of repeated exposure to Δ9‐tetrahydrocannabinol (Δ9‐THC) to produce long‐
lasting changes in synaptic connections in a manner similar to other drugs of abuse was …

Studies on 3, 4-methylenedioxymethamphetamine (“ecstasy”)-induced neurotoxicity mainly
focus on damage of serotonergic terminals. Less attention has been given to neuronal cell …

Recent theories on addiction implicate adaptive changes in prefrontal cortex (PFC) neurons
in reinforcing and psychotomimetic properties of psychostimulants, yet little is known about …

Morphine withdrawal produces a hypofunction of mesencephalic dopamine (DA) neurons
which impinge upon medium spiny neurons (MSN) of the forebrain. After chronic treatment …