Cxs (connexins), the protein subunits forming gap junction intercellular communication
channels, are transported to the plasma membrane after oligomerizing into hexameric …

Vertebrates express two families of gap junction proteins: the well characterized connexins
and the recently discovered pannexins. The latter are related to invertebrate innexins. Here …

Although human pannexins (PanX) are homologous to gap junction molecules, their
physiological function in vertebrates remains poorly understood. Our results demonstrate …

Connexin hemichannels have been proposed as a diffusion pathway for the release of
extracellular messengers like ATP and others, based on connexin expression models and …

Human bone marrow-derived mesenchymal stem cells (hMSCs) have the potential to
differentiate into several types of cells. Calcium ions (Ca2+) play an important role in the …

Gap junctional communication is important for embryonic morphogenesis. However, the
factors regulating the spatial properties of small molecule signal flows through gap junctions …

Gap junctions and/or paracrine mediators, such as ATP, mediate intercellular
communication (IC) in non-excitable cells. This study investigates the contribution of gap …

ATP's powerful impact on the heart and blood vessels was first described in 1929, but it was
not until the 1970s that ATP was proposed as the'purinergic'neurotransmitter in autonomic …

Human bone marrow-derived mesenchymal stem cells (hMSCs) have the potential to
differentiate into several types of cells. Calcium ions (Ca2+) play an important role in the …

The release of noradrenaline (NA) into the paraventricular nucleus (PVN) and supraoptic
nucleus (SON) is a critical step for enhanced magnocellular neuroendocrine cell (MNC) …