Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis

LF Barcellos, S Sawcer, PP Ramsay… - Human molecular …, 2006 - academic.oup.com
Variation in major histocompatibility complex genes on chromosome 6p21. 3, specifically the
human leukocyte antigen HLA-DR2 or DRB1* 1501-DQB1* 0602 extended haplotype …

Genetics of autoimmune neuroinflammation

T Olsson, M Jagodic, F Piehl, E Wallström - Current opinion in immunology, 2006 - Elsevier
Detection of gene variants affecting the risk for multiple sclerosis provides insights into
mechanisms central for autoaggressive neuroinflammation. Major histocompatibility …

Advanced intercross line mapping of Eae5 reveals Ncf-1 and CLDN4 as candidate genes for experimental autoimmune encephalomyelitis

K Becanovic, M Jagodic, JR Sheng… - The Journal of …, 2006 - journals.aai.org
Eae5 in rats was originally identified in two F 2 intercrosses,(DA× BN) and (E3× DA),
displaying linkage to CNS inflammation and disease severity in experimental autoimmune …

Human leukocyte antigen (HLA) DR15 is associated with reduced incidence of acute GVHD in HLA-matched allogeneic transplantation but does not impact chronic …

M Battiwalla, T Hahn, M Radovic, H Roy, A Wahab… - Blood, 2006 - ashpublications.org
The DR15 allele at the HLA DRB1 locus is a marker for immune-mediated bone marrow
failure syndromes. We hypothesized that HLA DR15 plays a role in T-cell interactions with …

Interaction of loci within the HLA region influences multiple sclerosis course in the Sardinian population

MG Marrosu, E Cocco, G Costa, MR Murru… - Journal of …, 2006 - Springer
We examined the influence of alleles at the HLA loci, previously found to be associated with
multiple sclerosis (MS) in Sardinia, on the clinical course of the disease in 835 relapsing (R) …

[HTML][HTML] A CX3CR1 genotype associated with retinal vasculitis in patients in the United Kingdom

GR Wallace, RW Vaughan, E Kondeatis… - … & visual science, 2006 - jov.arvojournals.org
purpose. To investigate whether polymorphisms in the gene encoding the chemokine
receptor CX 3 CR1, which has been linked to changes in functional ligand-binding activity …

Genetics: Susceptibility and expressivity

T Masterman, J Hillert - Handbook of multiple sclerosis, 2006 - taylorfrancis.com
It has long been recognized that, despite living at geographical latitudes where multiple
sclerosis (MS) is common, genetically isolated ethnic groups—including Gypsies in Hungary …

[PDF][PDF] Μελέτη των διαταραχών της ανοσολογικής απάντησης σε ασθενείς με σκλήρυνση κατά πλάκας

Β Τσιμούρτου - 2006 - ikee.lib.auth.gr
Η πολλαπλή σκλήρυνση είναι αυτοάνοση φλεγμονώδης νόσος που χαρακτηρίζεται από
απομυελίνωση και εκφύλιση του κεντρικού νευρικού συστήματος. Η αυτοάνοση παθογένεσή …

[图书][B] Clinical and MRI features of primary progressive multiple sclerosis

GT Ingle - 2006 - search.proquest.com
Abstract In approximately 10-15% of cases Multiple Sclerosis follows a progressive rather
than a relapsing course and this is known as Primary Progressive Multiple Sclerosis …