The cellular functions of the actin cytoskeleton require precise regulation of both the
initiation of actin polymerization and the organization of the resulting filaments. The actin …

Some development stages of the trypanosomatid protozoan parasites are well adapted to in
vitro culture. They can be maintained in rich medium containing large excess of glucose and …

Protozoan Kinetoplastida, including the pathogenic trypanosomatids of the genera
Trypanosoma and Leishmania, compartmentalize several important metabolic systems in …

Anthelmintic resistance is a major problem for the control of many parasitic nematode
species and has become a major constraint to livestock production in many parts of the …

The African trypanosome Trypanosoma brucei is best known for its extraordinarily
sophisticated antigenic variation of a protective variant surface glycoprotein (VSG) coat. T …

Trypanosoma brucei and the other members of the trypanosomatid family of parasitic
protozoa, contain an unusual RNA polymerase II enzyme, uncoordinated mRNA 5 …

Kinesin superfamily proteins are ubiquitous to all eukaryotes and essential for several key
cellular processes. With the establishment of genome sequence data for a substantial …

From early on in evolution, organisms have had to protect themselves from pathogens.
Mechanisms for discriminating “self” from “non‐self” evolved to accomplish this task …

The Trypanosoma brucei flagellum is unusual as it is attached along the cell body and
contains, in addition to an apparently conventional axoneme, a structure called the …

In total, 37080 protein sequences of the three trypanosomatids Leishmania major,
Trypanosoma brucei and Trypanosoma cruzi, were used to predict the trypanosomatid …