Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …

This book provides a comprehensive review of melancholia as a severe disorder of mood,
associated with suicide, psychosis, and catatonia. The syndrome is defined with a clear …

ContextPolymorphisms in the serotonin transporter gene (5-HTT) may influence
antidepressant response to selective serotonin reuptake inhibitors (SSRIs). The …

BACKGROUND: Antidepressant-induced mania (AIM) has been described in bipolar
disorder (BD) and has been associated with the short-allele of the serotonin transporter …

Methods: All spontaneous adverse drug reaction reports received by the Swedish Medical
Products Agency until December 1999 that were coded with EPS and judged to be at least …

Patients with bipolar disorder are at very high risk for suicidal ideation, non‐fatal suicidal
behaviors and suicide and are frequently treated with antidepressants. However, no …

Up to twenty percent of the American population suffers from a diagnosable mental disorder,
and cross-national studies suggest a high prevalence of such disorders elsewhere. In recent …

Objectives: To assess the influence of the serotonin transporter variable number of tandem
repeat (HTT-VNTR) polymorphism and the serotonin transporter-gene-linked polymorphic …

Although the field of pharmacogenetics has existed for nearly 50 years, it has begun to enter
mainstream clinical practice only recently. Researchers and clinicians have now …

Past research investigating the role of the serotonin transporter gene in OCD has produced
mixed findings. One possible reason for the mixed findings is comorbidity. In this study, non …