Grapefruit is rich in flavonoids, which have been demonstrated to have a preventive
influence on many chronic diseases, such as cancer and cardiovascular disease. However …

Therapeutic drug monitoring (TDM) and pharmacogenetic tests play a major role in
minimising adverse drug reactions and enhancing optimal therapeutic response. The …

The National Lipid Association's (NLA) Muscle Safety Expert Panel was charged with the
duty of examining the definitions, causative factors, and management of statin myopathy …

There is still an argument about ginseng–prescription drug interactions. To evaluate the
influence on cytochrome P450 (P450) activities of ginseng in the present study, the influence …

In our search for herbal remedies with inhibitory activity on cytochrome P450 (CYP)
enzymes, we identified extracts of the gum-resin of Boswellia carteri, Boswellia frereana …

Grapefruit juice (GFJ) has been found to interact with several medications, increasing their
oral bioavailability and the risk of toxicity. Inhibition of CYP3A4 in the small intestine by …

The potential inhibitory effect on P-glycoprotein (Pgp) by antiparasitic drugs and natural
compounds was investigated. Compounds were screened for Pgp interaction based on …

Since the introduction of cyclosporine to organ transplantation in the early 1980s,
therapeutic drug monitoring (TDM) has become an integral part of immunosuppressive drug …

Drug–drug interactions are commonly recognized occurrences in the hypertensive
population. Drug–nutrient interactions, however, are less well appreciated. The grapefruit …

Since the identification of all the major drug-metabolising cytochrome P450 (CYP) enzymes
and their major gene variants, pharmacogenetics has had a major impact on …