A perspective view of sodium iodide symporter research and its clinical implications
G Riesco-Eizaguirre… - European Journal of …, 2006 - academic.oup.com
The sodium iodide symporter (NIS) is an intrinsic plasma membrane protein that mediates
active iodide transport into the thyroid gland and into several extrathyroidal tissues, in …
active iodide transport into the thyroid gland and into several extrathyroidal tissues, in …
Cellular expression of monocarboxylate transporters (MCT) in the digestive tract of the mouse, rat, and humans, with special reference to slc5a8
T Iwanaga, K Takebe, I Kato, SI Karaki… - Biomedical …, 2006 - jstage.jst.go.jp
Short-chain fatty acids (SCFA) are monocarboxylates produced by bacterial fermentation
that play a crucial role in maintaining homeostasis in the large intestine. Two major …
that play a crucial role in maintaining homeostasis in the large intestine. Two major …
SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases
Tumor cells up-regulate glycolysis but convert pyruvate into lactate instead of oxidizing it.
Here, we show that pyruvate, but not lactate, is an inhibitor of histone deacetylases (HDAC) …
Here, we show that pyruvate, but not lactate, is an inhibitor of histone deacetylases (HDAC) …