Adipose tissue is responsive to both central and peripheral metabolic signals and is itself
capable of secreting a number of proteins. These adipocyte-specific or enriched proteins …

The risk factors for hypertension are only partly known, and accounts for the some of the
deficiencies in current primary prevention strategies and in the design of new drugs for the …

The understanding of the pathophysiology of atherosclerosis has advanced greatly in the
past decade. Cardiovascular risk factors increase the likelihood of an adverse event by …

Context: Postprandial hyperglycemia has been reported to elicit endothelial dysfunction and
provoke future cardiovascular complications. A reduction of postprandial blood glucose …

Metabolic syndrome (MS) is characterized by the presence of at least three of the following
alterations: enlargement of the waist diameter, higher levels of arterial pressure, low density …

Context: Endothelial dysfunction seems to be the first step of the atherosclerotic process. In
the past few years, it has been demonstrated that injured endothelial monolayer is restored …

The endothelium produces multiple mediators that not only regulate blood pressure, but also
important physiological inflammatory processes such as the recruitment and activation of …

Sildenafil citrate (Viagra®; Pfizer Inc, New York, NY) relaxes vascular smooth muscle,
resulting in modest reductions in blood pressure that are insufficient to stimulate a reflex …

The above-mentioned risk factors are a potential threat to the penile endothelium and the
smooth muscle tissue leading to functional and structural changes. These important …

We evaluated the effect of a chronic treatment with Tadalafil on progenitor cells (PCs)
number and endothelial function in patients with erectile dysfunction (ED) with or without …