The role of nicotinic acetylcholine receptors in Alzheimer's disease
S Oddo, FM LaFerla - Journal of Physiology-Paris, 2006 - Elsevier
The two hallmark lesions of Alzheimer's disease (AD) are extracellular amyloid plaques,
mainly formed by a small peptide called amyloid-β (Aβ), and neurofibrillary tangles, which …
mainly formed by a small peptide called amyloid-β (Aβ), and neurofibrillary tangles, which …
PET imaging of cortical 11C-nicotine binding correlates with the cognitive function of attention in Alzheimer's disease
A Kadir, O Almkvist, A Wall, B Långström… - …, 2006 - Springer
Abstract Rationale Patients suffering from Alzheimer's disease (AD) experience a marked
reduction in cortical nicotinic acetylcholine receptors (nAChRs). In particular, selective loss …
reduction in cortical nicotinic acetylcholine receptors (nAChRs). In particular, selective loss …
The induction of surface β-amyloid binding proteins and enhanced cytotoxicity in cultured PC-12 and IMR-32 cells by advanced glycation end products
S Mruthinti, A Sood, CL Humphrey, S Swamy-Mruthinti… - Neuroscience, 2006 - Elsevier
During aging the non-enzymatic glycation of proteins and other molecules increases
significantly, leading to the accumulation of advanced glycation end-products (AGEs). These …
significantly, leading to the accumulation of advanced glycation end-products (AGEs). These …
The N-butylcarbamate derivative of galantamine acts as an allosteric potentiating ligand on [alpha] 7 nicotinic receptors in hippocampal neurons
RV Popa, F Edna, R Pereira, C Lopes… - Journal of …, 2006 - search.proquest.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by
cognitive impairments that become severe enough to interfere with the daily activities of …
cognitive impairments that become severe enough to interfere with the daily activities of …
Autoradiography of 2‐[18F]F‐A‐85380 on nicotinic acetylcholine receptors in the porcine brain in vitro
W Deuther‐Conrad, A Wevers, G Becker, A Schildan… - Synapse, 2006 - Wiley Online Library
Noninvasive molecular imaging of subtypes of neuronal nicotinic acetylcholine receptors
(nAChRs) will provide information on the role of these receptors in neurodegenerative …
(nAChRs) will provide information on the role of these receptors in neurodegenerative …
[图书][B] Interactive mechanism between beta-amyloid process, alfa7 nicotinic receptor, glial cell activation and oxidative stress in Alzheimer's disease
WF Yu - 2006 - search.proquest.com
Alzheimer's disease (AD) is the most common form of dementia with pathological features
including the accumulation of neuritic plaques (NPs) and neurofibrillary tangles (NFTs) …
including the accumulation of neuritic plaques (NPs) and neurofibrillary tangles (NFTs) …
[图书][B] Modulation of sympathetic α7-nicotinic acetylcholine receptor by cholinesterase inhibitors and statins
M Mozayan - 2006 - search.proquest.com
Cholinesterase inhibitors (ChEIs) have been used to treat Alzheimer's disease (AD). The
efficacy of these drugs, however, is less than satisfactory. The possibility that ChEIs may …
efficacy of these drugs, however, is less than satisfactory. The possibility that ChEIs may …