MIF: a new cytokine link between rheumatoid arthritis and atherosclerosis

EF Morand, M Leech, J Bernhagen - Nature reviews Drug discovery, 2006 - nature.com
Macrophage migration inhibitory factor (MIF) is well established as a key cytokine in immuno-
inflammatory diseases such as rheumatoid arthritis. Inflammation is now also recognized as …

Die Rolle des Macrophage Migration Inhibitory Factor bei inflammatorischen Immunantworten und der rheumatoiden Arthritis

LL Santos, EF Morand - Wiener Medizinische Wochenschrift, 2006 - Springer
Die rheumatoide Arthritis (RA) ist eine Erkrankung unbekannter Ätiologie, welche mit
schweren Behinderungen einhergehen kann. Obwohl die Pathogenese der RA …

Reduction of the aortic inflammatory response in spontaneous atherosclerosis by blockade of macrophage migration inhibitory factor (MIF)

A Burger-Kentischer, H Göbel, R Kleemann… - Atherosclerosis, 2006 - Elsevier
Atherosclerosis is an inflammatory response of the arterial wall to “injury”, which is
prominently driven by cytokines. The inflammatory mediator macrophage migration …

Macrophage migration inhibitory factor deficiency attenuates macrophage recruitment, glomerulonephritis, and lethality in MRL/lpr mice

AY Hoi, MJ Hickey, P Hall, J Yamana… - The Journal of …, 2006 - journals.aai.org
Systemic lupus erythematosus (SLE) is a serious systemic autoimmune disease of unknown
etiology. Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine that is …

Tumor-derived macrophage migration inhibitory factor (MIF) inhibits T lymphocyte activation

X Yan, RJ Orentas, BD Johnson - Cytokine, 2006 - Elsevier
Macrophage migration inhibitory factor (MIF) is a multi-functional cytokine that is considered
a pro-inflammatory cytokine. However, our studies show that MIF, when produced in super …

Neutralization of macrophage migration inhibitory factor—novel approach for the treatment of immunoinflammatory disorders

I Cvetkovic, S Stosic-Grujicic - International immunopharmacology, 2006 - Elsevier
Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine that plays an
important role in the pathogenesis of numerous inflammatory and autoimmune disorders. As …

Macrophage migration inhibitory factor in zinc-allergic systemic contact dermatitis

T Yanagi, K Kodama, Y Yoshihisa, H Shimizu… - Cytokine, 2006 - Elsevier
Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine whose
expression has been found to be critical to the generation of the antigen-specific immune …

Effect of macrophage migration inhibitory factor (MIF) on acute graft-versus-host disease in a murine model of allogeneic stem cell transplantation

T Toubai, J Tanaka, J Nishihira, T Ohkawara… - Transplant …, 2006 - Elsevier
Macrophage migration inhibitory factor (MIF) may play an important role in the pathogenesis
of acute graft-versus-host disease (aGVHD) after allogeneic hematopoietic stem cell …

Cytokines: stress and immunity

RE Faith, AJ Murgo, RA Good, NP Plotnikoff - 2006 - taylorfrancis.com
Cytokine involvement in the immune system's response to stress is now very well
documented. Cytokine activity has been implicated in a variety of mental and physical …

MIF and the genetic basis of macrophage responsiveness

R Bucala - Current Immunology Reviews, 2006 - ingentaconnect.com
Macrophage migration inhibitory factor (MIF) describes one of the first cytokine activities to
be discovered, but the precise role of this immunologic mediator in the host response only …