Nature and significance of the interactions between amyloid fibrils and biological polyelectrolytes

M Calamai, JR Kumita, J Mifsud, C Parrini… - Biochemistry, 2006 - ACS Publications
Charged polyelectrolytes such as glycosaminoglycans and nucleic acids have frequently
been found associated with the proteinaceous deposits in the tissues of patients with …

Role of protein conformational dynamics and DNA integrity in relevance to neuronal cell death in neurodegeneration

V Bala Gupta, ML Hegde… - Current Alzheimer …, 2006 - ingentaconnect.com
Apoptosis has been implicated in the pathogenesis of various neurodegenerative disorders,
although the extent to which it is responsible for the neurodegeneration along with other …

Genotoxicity in Alzheimer's disease: role of amyloid

A Suram, C Venugopal, A Prakasam… - Current Alzheimer …, 2006 - ingentaconnect.com
Alzheimer's disease (AD) is a complex neurodegenerative disorder pathologically identified
by the presence of extracellular senile plaques (SP) with a proteinaceous core composed of …