Two fundamentally different views of how proteins fold are now being debated. Do proteins
fold through multiple unpredictable routes directed only by the energetically downhill nature …

Biological systems often transport charges and reactive processes over substantial
distances. Traditional models of chemical kinetics generally do not describe such extreme …

Domains are basic evolutionary units of proteins and most proteins have more than one
domain. Advances in domain modeling and collection are making it possible to annotate a …

Motivation: Most methods that are used to compare protein structures use three-dimensional
(3D) structural information. At the same time, it has been shown that a 1D string …

Previous results indicate that the folding pathways of cytochrome c and other proteins
progressively build the target native protein in a predetermined stepwise manner by the …

Studies of circular permutants have demonstrated that the folding reaction of S6 from
Thermus thermophilus (S6T) is malleable and responds in an ordered manner to changes of …

O2carriers (extracellular and intracellular as well as monomeric and multimeric) have
evolved over the last billion of years, displaying iron and copper reactive centers; very …

Abstract Biologische Systeme transportieren Ladungen und reaktive Prozesse häufig über
beträchtliche Entfernungen. Traditionelle Modelle der chemischen Kinetik können solche …

The stabilization energy of proteins in their native conformation is not distributed uniformly
among all the amino acids, but is concentrated in few (short) fragments, fragments which …

To understand how protein reduces the conformational space to be searched for the native
structure, it is crucial to characterize ensembles of conformations on the way of folding …