Liposome-encapsulated Hb (LEH) is being developed as an artificially assembled, low-
toxicity, and spatially isolated Hb-based oxygen carrier (HBOC). Standard methods of …

Hb-vesicles (HbV) are artificial oxygen carriers that encapsulate purified Hb solution (35
g/dl) in unilamellar phospholipid vesicles (liposomes). The dispersion stability of HbV is …

The delivery of oxygen to tissue by cell-free carriers eliminates intraluminal barriers
associated with red blood cells. This is important in arterioles, since arteriolar tone controls …

This paper describes the approaches we have taken to construct a) mutant hemoglobins
with different oxygen affinities, and b) mutant hemoglobins and myoglobins that polymerize …

Despite the advances in blood substitutes, the development of materials that are effective in
maintaining blood volume and oxygen delivery remains the priority for emergency care and …

Hemoglobin-vesicles (HbV) or liposome-encapsulated Hb are artificial oxygen carriers. Our
previous studies of the bolus infusion of HbV into Wistar rats showed that HbV was captured …

In this study capillary zone electrophoresis (CZE) was used to analyze the poly (ethylene
glycol)-modified bovine hemoglobin (PEG-bHb). The results show that CZE separated the …

Hemoglobin vesicles (HbV), or liposome‐encapsulated hemoglobins, are developed as
artificial oxygen carriers for the use as a transfusion alternative. The safety and efficacy of …

Background.-Formed from a lipid bilayer membrane, hemoglobin vesicle (HbV) is a small
sphere (diameter ca. 250 nm) which contains hemoglobin, and is a candidate blood …

Das Ziel bei der Entwicklung künstlicher Sauerstoffträger ist es, die
Sauerstofftransportkapazität des Blutes zu steigern, um dadurch unter kritischen …