Activation of a novel ataxia-telangiectasia mutated and rad3 related/checkpoint kinase 1–dependent prometaphase checkpoint in cancer cells by diallyl trisulfide, a …
A Herman-Antosiewicz, SD Stan, ER Hahm… - Molecular cancer …, 2007 - AACR
Diallyl trisulfide (DATS), a cancer chemopreventive constituent of garlic, inhibits growth of
cancer cells by interfering with cell cycle progression, but the mechanism is not fully …
cancer cells by interfering with cell cycle progression, but the mechanism is not fully …
Control of the yeast telomeric senescence survival pathways of recombination by the Mec1 and Mec3 DNA damage sensors and RPA
N Grandin, M Charbonneau - Nucleic acids research, 2007 - academic.oup.com
Saccharomyces cerevisiae telomerase-negative cells undergo homologous recombination
on subtelomeric or TG 1–3 telomeric sequences, thus allowing Type I or Type II post …
on subtelomeric or TG 1–3 telomeric sequences, thus allowing Type I or Type II post …
Activation of the Budding Yeast Securin Pds1 But Not Rad53 Correlates with Double-Strand Break-Associated G2/M Cell Cycle Arrest in a mec1 Hypomorphic …
M Sun, M Fasullo - Cell Cycle, 2007 - Taylor & Francis
Budding yeast Mec1, encoded by the yeast ATR/ATM homolog, negatively regulates cell
cycle progression by activating Rad53 (Chk2) and Chk1, two parallel downstream …
cycle progression by activating Rad53 (Chk2) and Chk1, two parallel downstream …
Non-catalytic function for ATR in the checkpoint response
The ATR family of checkpoint kinases is essential for an appropriate response to genomic
insults in eukaryotes. Included in this family are Mei-41 in Drosophila, Mec1 in S. cerevisiae …
insults in eukaryotes. Included in this family are Mei-41 in Drosophila, Mec1 in S. cerevisiae …
Activation of repair and checkpoints by double-strand breaks of DNA. Activational cascade of protein phosphorylation
NA Koltovaya - 2007 - inis.iaea.org
[en] Molecular mechanisms of double-strand breaks repair and checkpoints include
phosphorylations of repair and checkpoint-proteins by protein kinases. Chemical …
phosphorylations of repair and checkpoint-proteins by protein kinases. Chemical …
Interactions of checkpoint-genes RAD9, RAD17, RAD24, RAD53 with genes SRM5/CDC28, SRM8/NET1 and SRM12/HF11 in determining radioresistance of yeast …
NA Koltovaya, YV Nikulushkina, EY Kadyshevskaya… - 2007 - inis.iaea.org
[en] In yeast Saccharomyces cerevisiae checkpoint-genes RAD9, RAD17, RAD24, RAD53
and genes SRM5/CDC28, SRM8/NET1, SRM12/HF11 have been found to belong to one …
and genes SRM5/CDC28, SRM8/NET1, SRM12/HF11 have been found to belong to one …
[图书][B] The involvement of single-stranded DNA, replication protein A, and the DNA double-strand break dose in the damage checkpoint of Saccharomyces cerevisiae
C Zierhut - 2007 - search.proquest.com
In response to DNA damage, eukaryotic cells activate a checkpoint signalling cascade,
resulting in cell cycle arrest, stabilisation of replication forks and activation of repair. While …
resulting in cell cycle arrest, stabilisation of replication forks and activation of repair. While …
[图书][B] Phosphorylation induced intersubunit interactions in replication protein A
SK Binz - 2007 - search.proquest.com
Replication protein A (RPA) is the eukaryotic single-stranded DNA-binding protein. RPA
homologues have been found in all eukaryotes examined and are essential for multiple …
homologues have been found in all eukaryotes examined and are essential for multiple …
Cooperative nuclease activity of the Mre11/Rad50/Xrs2 complex and Sae2 during DNA double-strand break repair
BM Lengsfeld - 2007 - repositories.lib.utexas.edu
DNA double-strand breaks (DSBs) are lethal in eukaryotic cells if left unrepaired. In
Saccharomyces cerevisiae the Mre11/Rad50/Xrs2 (MRX) complex is required for repair of …
Saccharomyces cerevisiae the Mre11/Rad50/Xrs2 (MRX) complex is required for repair of …