Cutaneous leishmaniasis is endemic in the tropics and neotropics. It is often referred to as a
group of diseases because of the varied spectrum of clinical manifestations, which range …

Visceral leishmaniasis (VL) is a systemic protozoan disease that is transmitted by
phlebotomine sandflies. Poor and neglected populations in East Africa and the Indian sub …

Leishmania parasites cause a broad spectrum of clinical disease. Here we report the
sequencing of the genomes of two species of Leishmania: Leishmania infantum and …

Leishmaniases remain a major public health problem today despite the vast amount of
research conducted on Leishmania pathogens. The biological model is genetically and …

Gene expression in Kinetoplastids is very unusual in that the open reading frames are
arranged in long polycistronic arrays, monocistronic mRNAs being created by post …

Dyneins are large minus‐end‐directed microtubule motors. Each dynein contains at least
one dynein heavy chain (DHC) and a variable number of intermediate chains (IC), light …

Leishmania amastigotes primarily proliferate within macrophages in the mammalian host.
Genome-based metabolic reconstructions, combined with biochemical, reverse genetic and …

Leishmania are protozoan parasites that cause a wide spectrum of clinical diseases in
humans and are a major public health risk in several countries. Leishmania life cycle …

The calpain family is named for the calcium dependence of the papain-like, thiol protease
activity of the well-studied ubiquitous vertebrate enzymes calpain-1 (μ-calpain) and calpain …

Kinetoplastids branched early from the eukaryotic lineage and include several parasitic
protozoan species. Up to several hundred kinetoplastid genes are co-transcribed into …