Screening of protease inhibitors as antiplasmodial agents. Part I: Aziridines and epoxides
F Schulz, C Gelhaus, B Degel, R Vicik… - ChemMedChem …, 2007 - Wiley Online Library
A broad protease‐based and cell‐based screening of protease inhibitors yielded the
aziridine‐2‐carboxylic acid derivative 2 a and the N‐acylated aziridine‐2, 3‐dicarboxylic …
aziridine‐2‐carboxylic acid derivative 2 a and the N‐acylated aziridine‐2, 3‐dicarboxylic …
Total synthesis of miraziridine A and identification of its major reaction site for cathepsin B
H Konno, K Kubo, H Makabe, E Toshiro, N Hinoda… - Tetrahedron, 2007 - Elsevier
The synthesis of miraziridine A, a pentapeptide derivative isolated from marine sponge, and
its truncated analogs has been achieved. To construct the backbone of miraziridine A, a side …
its truncated analogs has been achieved. To construct the backbone of miraziridine A, a side …
Electron‐Density Determination of Electrophilic Building Blocks as Model Compounds for Protease Inhibitors
S Grabowsky, T Pfeuffer, L Chęcińska, M Weber… - 2007 - Wiley Online Library
Three types of synthesised compounds, the aziridine 1, the epoxide 2 and the acceptor‐
substituted olefin 3, were chosen as model compounds for electrophilic building blocks …
substituted olefin 3, were chosen as model compounds for electrophilic building blocks …