“Vulnerable” plaques are atherosclerotic plaques that have a high likelihood to cause
thrombotic complications, such as myocardial infarction or stroke. Plaques that tend to …

The vulnerability or destabilization of atherosclerotic plaques has been directly linked to
plaque composition. Imaging modalities, such as magnetic resonance (MR) imaging, that …

Inflammation plays a major role in all phases of atherosclerosis. Stable plaques are
characterized by a chronic inflammatory infiltrate, whereas vulnerable and ruptured plaques …

Background and Purpose—Carotid intraplaque hemorrhage (IPH), known to be associated
with plaque instability, may convey a higher stroke risk. The aim of this study was to assess …

Objectives: The Computer-Aided System for CArdiovascular Disease Evaluation
(CASCADE) has been developed for streamlined, automated analysis of carotid artery …

The pathological remodeling of the arterial wall in atherosclerosis involves protease
activities, which play a major role in complications via plaque rupture. Circulating leukocytes …

Only a minority of patients with carotid arterial disease have warning symptoms, because the
majority of strokes are caused by previously asymptomatic lesions. Because morbidity and …

Angiogenesis within human atherosclerotic plaques has an important role in plaque
progression as immature blood vessels leak red blood cells and inflammatory mediators into …

Emerging data suggest that intraplaque hemorrhage is critical in promoting atherosclerotic
lesion instability. Because red blood cell membranes are a rich source of free cholesterol …

Free cholesterol in atherosclerotic plaques: where does it c... : Current Opinion in Lipidology
Free cholesterol in atherosclerotic plaques: where does it come from? : Current Opinion in …