Objective. Previous studies have reported an overlap between gastroesophageal reflux
symptoms, functional dyspepsia (FD) and irritable bowel syndrome (IBS). The aim of this …

Background Twenty per cent of patients with heartburn do not respond to proton pump
inhibitors (PPIs). Many have normal oesophageal acid exposure. We hypothesized that such …

Emerging information on physiology and pathophysiology of gastroesophageal reflux
disease raises the question of whether our thought process should go beyond mucosal …

BACKGROUND: The pathophysiology of persistent gastroesophageal reflux disease
(GERD) symptoms after antireflux surgery is unclear. We assessed esophageal …

Concepts of the spectrum of gastroesophageal reflux disease (GERD) continue to evolve as
researchers and clinicians challenge conceptual frameworks and explore new paradigms …

Gastroesophageal reflux disease (GERD) is a very common disorder, characterized by
symptoms and lesions that are attributable to reflux of gastric content into the esophagus …

Nonerosive reflux disease (NERD) is defined as the presence of classic symptoms of
gastrooesophageal reflux disease (GORD) in the absence of oesophageal mucosal injury …

Gastroesophageal reflux disease (GERD) is a common burden on health careresources in
the Western world and deteriorates the health-relatedquality of life of those affected, but its …